This year, up to 2 million Americans will contract drug-resistant bacterial infections. Microbiologist and immunologist Silvia Caballero wants to do something about that. After graduating from Weill Cornell Medical College in 2009 and going to work at Memorial Sloan Kettering Cancer Center, she developed a type of lab mouse whose gut replicates the human systems infected by drug-resistant bugs. She then turned the bodies of the mice against the invaders, discovering natural bacteria within the gut that could beat back the infection. Now working for Vedanta Biosciences in Massachusetts, she heads the company’s multidrug-resistant organism decolonization program, whose goal is to do for people what Caballero did for the mice. Her treatment protocol could go into early trials in two years. —Jeffrey Kluger
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Camila CabelloHenry GoldingLiza KoshyLili ReinhartJason ReynoldsMaggie RogersRyan O'ConnellAli StrokerBeanie FeldsteinMj RodriguezJharrel JeromeD.J. "Shangela" PierceWanuri KahiuBillie EilishBowen YangNjideka Akunyili CrosbyEzra MillerMegan Thee StallionJohn EdmondsNoah CentineoAdvocates
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Full List
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Camila CabelloHenry GoldingLiza KoshyLili ReinhartJason ReynoldsMaggie RogersRyan O'ConnellAli StrokerBeanie FeldsteinMj RodriguezJharrel JeromeD.J. "Shangela" PierceWanuri KahiuBillie EilishBowen YangNjideka Akunyili CrosbyEzra MillerMegan Thee StallionJohn EdmondsNoah CentineoAdvocates
AwkwafinaBad BunnyChanel MillerKwame OnwuachiAsia Kate DillonCamille FrançoisBindi Irwin and Robert IrwinAmanda NguyenMagid MagidAdut AkechAlexandra RojasGina MartinVijay GuptaToby MerrillDutee ChandJoy BuolamwiniSara MardiniXiuhtezcatl Martinez and Kelsey JulianaOluwaseun Ayodeji OsowobiLeaders
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Zion WilliamsonAlysa LiuLil Nas XKeke PalmerSally RooneyCoco GauffBen StokesJeremy O. HarrisTim EllisBlackpinkEmma ChamberlainMarsai MartinRegan SmithKerby Jean-RaymondBobi WineMax SchremsInnovators
Emily WeissLilly SinghDesus and MeroNite YunJess Morales RockettoMelina MatsoukasAudrey GelmanBrian ArmstrongTristan WalkerNat Turner and Zach WeinbergMei Mei HuKeller RinaudoHenrique Dubugras and Pedro FranceschiVarun SivaramYuan CaoSilvia CaballeroKotchakorn VoraakhomPaula JofréJayathma WickramanayakeArtists
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Leaders
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Camila CabelloHenry GoldingLiza KoshyLili ReinhartJason ReynoldsMaggie RogersRyan O'ConnellAli StrokerBeanie FeldsteinMj RodriguezJharrel JeromeD.J. "Shangela" PierceWanuri KahiuBillie EilishBowen YangNjideka Akunyili CrosbyEzra MillerMegan Thee StallionJohn EdmondsNoah CentineoAdvocates
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Carlos Alvarado QuesadaAly RaismanPete ButtigiegElise StefanikJosh HawleyLauren UnderwoodKyrsten SinemaVarshini PrakashFrancis SuarezDan CrenshawEdward LeungJesse KlaverJordan BardellaVanessa LunaAyman OdehNadiem MakarimRafaela RequesensRoya RahmaniShinjiro KoizumiTabata AmaralThanathorn JuangroongruangkitPhenoms
Zion WilliamsonAlysa LiuLil Nas XKeke PalmerSally RooneyCoco GauffBen StokesJeremy O. HarrisTim EllisBlackpinkEmma ChamberlainMarsai MartinRegan SmithKerby Jean-RaymondBobi WineMax SchremsInnovators
Emily WeissLilly SinghDesus and MeroNite YunJess Morales RockettoMelina MatsoukasAudrey GelmanBrian ArmstrongTristan WalkerNat Turner and Zach WeinbergMei Mei HuKeller RinaudoHenrique Dubugras and Pedro FranceschiVarun SivaramYuan CaoSilvia CaballeroKotchakorn VoraakhomPaula JofréJayathma WickramanayakeTIME may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.