David Sinclair

Sinclair, from Harvard Medical School, is testing a pill that appears to address and even reverse some of the typical signs of aging, including higher blood pressure, weight gain and slower metabolism­—at least in mice. This year Sinclair found in the animals an even more tantalizing benefit: the compound can also serve as exercise in a pill, reversing aging in blood vessels and “working out” muscles as if they had been on a treadmill. Human trials are set to start in the next year or so. —Alice Park