Sinclair, from Harvard Medical School, is testing a pill that appears to address and even reverse some of the typical signs of aging, including higher blood pressure, weight gain and slower metabolism—at least in mice. This year Sinclair found in the animals an even more tantalizing benefit: the compound can also serve as exercise in a pill, reversing aging in blood vessels and “working out” muscles as if they had been on a treadmill. Human trials are set to start in the next year or so. —Alice Park
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