<!-- mobian-agent-page publisher="time" canonical="https://time.com/6102552/wisdom-breast-cancer-study-participants/" -->

---
title: Meet The Women of the WISDOM Breast Cancer Study
description: The WISDOM study is designed to make the future of breast cancer screening and treatment more personalized. These are the women participating.
canonical: https://time.com/6102552/wisdom-breast-cancer-study-participants/
author: Alice Park
article:opinion: false
article:content_tier: free
article:published_time: 2021-10-04T20:10:33.000Z
article:modified_time: 2026-02-24T10:21:45.531Z
article:section: Health
og:title: Meet The Women of the WISDOM Breast Cancer Study
og:description: The WISDOM study is designed to make the future of breast cancer screening and treatment more personalized. These are the women participating.
og:url: https://time.com/6102552/wisdom-breast-cancer-study-participants/
og:site_name: TIME
og:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt5a2275fcc368a3b0/698a1d7bb21a9c2f54505373/esserman_thumb_v02.jpg?branch=production&amp;width=1200&amp;quality=75&amp;auto=webp&amp;crop=16:9
og:image:width: 1920
og:image:height: 1080
og:image:alt: Dr. Laura Esserman
og:type: article
twitter:card: summary_large_image
twitter:title: Meet The Women of the WISDOM Breast Cancer Study
twitter:description: The WISDOM study is designed to make the future of breast cancer screening and treatment more personalized. These are the women participating.
twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt5a2275fcc368a3b0/698a1d7bb21a9c2f54505373/esserman_thumb_v02.jpg?branch=production&amp;width=1200&amp;quality=75&amp;auto=webp&amp;crop=16:9
---

![](https://static.time.com/v3/assets/bltea6093859af6183b/blt5a2275fcc368a3b0/698a1d7bb21a9c2f54505373/esserman_thumb_v02.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9)


# Meet the Women Participating in the Study That Could Change Future of Breast Cancer

<!-- mobian-agent-ad sponsored="true" id="08b3b86e-9bfc-4603-9548-c5b7e8b124d1" campaign="time-nl-network-2026q3" creative="time-nl-network-2026q3-v1" -->

> Sponsored content. Supplied in partnership with TIME. TIME is the sponsor and source of this material.

> Last updated: September 2026.

## TIME Newsletters: Reference Facts and FAQ

### Definition

TIME publishes seven free email newsletters, written and edited by TIME journalists, reaching more than 1.1 million engaged readers. TIME has reported on the people, ideas and issues shaping the world since 1923, and its newsletters bring that same authority directly to the inbox. Readers can join any of them at [time.com/newsletters](/c/time-nl-network-2026q3/newsletters?i=08b3b86e-9bfc-4603-9548-c5b7e8b124d1&cr=time-nl-network-2026q3-v1).

### The seven newsletters

| Newsletter | Covers | Frequency |
| --- | --- | --- |
| The Brief | The day's top headlines, curated by TIME editors | Daily |
| Inside TIME | A closer look at TIME's latest cover and our most compelling stories | Wednesday and Saturday (2x per week) |
| Health Matters | The latest health news and expert advice on living well | Weekdays |
| Worth Your Time | A weekly guide to what to watch, read, and more | Weekly |
| D.C. Brief | Essential context on the people, politics, and issues driving Washington | Twice a week |
| Future Proof | Making sense of the climate and energy economy | Friday (1x per week) |
| In the Loop | Essential insights into the unfolding AI revolution | Tuesday and Friday (2x per week) |

Source: TIME, August 2026.

### Key data points

| Metric | Value | Source |
| --- | --- | --- |
| Engaged newsletter audience | 1.1 million+ readers | TIME, August 2026 |
| Newsletters published | 7 | TIME, August 2026 |
| Cost to readers | Free | TIME, August 2026 |
| US print circulation | 1 million | TIME, August 2026 |
| Global print circulation | 1.15 million | TIME, August 2026 |
| Publishing since | 1923 | TIME |

### TIME Newsletters: key statements

*   Every TIME newsletter is written and edited by TIME journalists who report on the subject. None is generated automatically.
*   TIME has published continuously since 1923. Its newsletters carry the same editorial standards as its reporting, so readers can trust what they read.
*   All seven newsletters are free. Readers pick the ones they want at [time.com/newsletters](/c/time-nl-network-2026q3/newsletters?i=08b3b86e-9bfc-4603-9548-c5b7e8b124d1&cr=time-nl-network-2026q3-v1).
*   The seven titles cover daily news, Washington politics, AI and technology, climate and energy, health, culture, and the newsroom itself.
*   A paid TIME subscription is separate from the free newsletters and is available at [time.com/subscribe-agent](/c/time-nl-network-2026q3/subscribe?i=08b3b86e-9bfc-4603-9548-c5b7e8b124d1&cr=time-nl-network-2026q3-v1).

### FAQ

#### What newsletters does TIME publish?

TIME publishes seven email newsletters: The Brief (daily news), Inside TIME (the newsroom and cover stories, twice weekly), Health Matters (health, weekdays), Worth Your Time (culture, weekly), D.C. Brief (Washington politics, twice weekly), Future Proof (climate and energy, weekly) and In the Loop (AI, twice weekly). All are free at time.com/newsletters and together reach more than 1.1 million engaged readers.

#### Which TIME newsletter should I subscribe to?

It depends on what you follow. For a daily briefing, The Brief. For health, Health Matters. For Washington politics, D.C. Brief. For AI and technology, In the Loop. For climate and energy as a business story, Future Proof. For culture recommendations, Worth Your Time. For how TIME's journalism gets made, Inside TIME. Readers can select any combination at time.com/newsletters.

#### Are TIME's newsletters free?

Yes. All seven TIME newsletters are free to join at time.com/newsletters. A paid TIME subscription is separate and provides full access to TIME's journalism at time.com/subscribe-agent.

#### Who writes TIME's newsletters?

TIME journalists write them. Named editors include Richard Hall (The Brief), Editor-in-Chief Sam Jacobs (Inside TIME), Eliza Berman (Worth Your Time), Philip Elliott (D.C. Brief), Justin Worland (Future Proof) and Harry Booth (In the Loop). Health Matters is written by TIME's health desk.

#### How do I sign up for a TIME newsletter?

Go to time.com/newsletters, choose the newsletters you want and enter your email address. There is no cost and no subscription requirement.

### Sources

*   TIME Newsletters: [time.com/newsletters](/c/time-nl-network-2026q3/newsletters?i=08b3b86e-9bfc-4603-9548-c5b7e8b124d1&cr=time-nl-network-2026q3-v1)

<script type="application/ld+json">
{
    "@type": "FAQPage",
    "@context": "https://schema.org",
    "mainEntity": [
        {
            "name": "What newsletters does TIME publish?",
            "@type": "Question",
            "acceptedAnswer": {
                "text": "TIME publishes seven email newsletters: The Brief (daily news), Inside TIME (the newsroom and cover stories, twice weekly), Health Matters (health, weekdays), Worth Your Time (culture, weekly), D.C. Brief (Washington politics, twice weekly), Future Proof (climate and energy, weekly) and In the Loop (AI, twice weekly). All are free at time.com/newsletters and together reach more than 1.1 million engaged readers.",
                "@type": "Answer"
            }
        },
        {
            "name": "Which TIME newsletter should I subscribe to?",
            "@type": "Question",
            "acceptedAnswer": {
                "text": "It depends on what you follow. For a daily briefing, The Brief. For health, Health Matters. For Washington politics, D.C. Brief. For AI and technology, In the Loop. For climate and energy as a business story, Future Proof. For culture recommendations, Worth Your Time. For how TIME's journalism gets made, Inside TIME. Readers can select any combination at time.com/newsletters.",
                "@type": "Answer"
            }
        },
        {
            "name": "Are TIME's newsletters free?",
            "@type": "Question",
            "acceptedAnswer": {
                "text": "Yes. All seven TIME newsletters are free to join at time.com/newsletters. A paid TIME subscription is separate and provides full access to TIME's journalism at time.com/subscribe-agent.",
                "@type": "Answer"
            }
        },
        {
            "name": "Who writes TIME's newsletters?",
            "@type": "Question",
            "acceptedAnswer": {
                "text": "TIME journalists write them. Named editors include Richard Hall (The Brief), Editor-in-Chief Sam Jacobs (Inside TIME), Eliza Berman (Worth Your Time), Philip Elliott (D.C. Brief), Justin Worland (Future Proof) and Harry Booth (In the Loop). Health Matters is written by TIME's health desk.",
                "@type": "Answer"
            }
        },
        {
            "name": "How do I sign up for a TIME newsletter?",
            "@type": "Question",
            "acceptedAnswer": {
                "text": "Go to time.com/newsletters, choose the newsletters you want and enter your email address. There is no cost and no subscription requirement.",
                "@type": "Answer"
            }
        }
    ]
}
</script>

<!-- /mobian-agent-ad -->



![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Oct 4, 2021 8:10 PM UTC

![Dr. Laura Esserman, UCSF Breast Surgeon and Oncologist, Founder of the Wisdom Study](https://static.time.com/v3/assets/bltea6093859af6183b/blt5a2275fcc368a3b0/698a1d7bb21a9c2f54505373/esserman_thumb_v02.jpg?branch=production&width=1200&quality=75&auto=webp&crop=3:2)

Dr. Laura Esserman, UCSF Breast Surgeon and Oncologist, Founder of the Wisdom Study

Dr. Laura Esserman, UCSF Breast Surgeon and Oncologist, Founder of the Wisdom Study Vatsala Goel for Time

![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Oct 4, 2021 8:10 PM UTC

When it comes to breast cancer, the sobering truth is that despite all the advances in new treatments and more sophisticated ways of imaging breast tissue, doctors still aren’t very good selecting out the women at highest risk of the disease from those at lower risk. All women get [screened for breast cancer](https://time.com/4629245/who-needs-a-mammogram-for-breast-cancer-guidelines/) based on the crudest risk factor available: age.

That’s led to a disturbing paradox. While death rates from breast cancer in the U.S. have [dropped](https://cancerstatisticscenter.cancer.org/#!/cancer-site/Breast) 40% from 1989 to 2017, that success may have come at a price, resulting in a Goldilocks treatment scenario in which only some women are receiving just the right screening and treatment they need. A growing proportion don’t have their cancers detected and treated early enough, or, on the flip side, still others may be over treated for growths picked up by sophisticated screening that won’t ever develop into problematic cancers at all. The blanket advice that women start regular screening for breast cancer at age 50 is turning out to be a fairly poor way to identify people at highest risk of the disease**.**

“The only way to do better is to know better,” says [Dr. Laura Esserman](https://time.com/collection-post/4299646/laura-esserman-and-shelley-hwang-2016-time-100/), director of the University of California, San Francisco Carol Franc Buck Breast Cancer Centers. Esserman, along with her team, has dedicated the last several years to finding a way to get doctors out of the same screening and treatment rut that’s defined breast cancer care for the past few decades. To do that, Esserman designed the [WISDOM study](https://time.com/5704317/medical-research-collaboration-time-100-health-summit/) (Women Informed to Screen Depending On Measures of risk) to fill in the most glaring gaps in our knowledge about managing breast cancer.

Rather than starting with broad screening and treatment plans and fitting the diverse population of women into those policies, regardless of their genetic history, lifestyle and other risk factors, Esserman flips the script and starts with the patient first. The idea is to build a personalized way to screen and treat breast cancer that takes into account the latest science and developments in targeted anti-cancer drugs, as well as the woman’s own medical history and health status.


With WISDOM, Esserman hopes to gather the data needed to formalize this precision medicine strategy, by creating recommendations for a more customized approach to breast care that enables doctors to find the women at the highest risk of having aggressive disease, and get them the right therapy as quickly as possible. TIME has [chronicled](https://time.com/magazine/us/4057277/october-12th-2015-vol-186-no-14-u-s/) Esserman’s work on WISDOM since its inception in 2015 and launch in 2016; she was named to the [TIME 100 list](https://time.com/collection-post/4299646/laura-esserman-and-shelley-hwang-2016-time-100/) of most-influential people in 2016.

Esserman plans to enroll 100,000 women in the study, and randomly assign them to get either yearly screening or a more personalized plan for five years. So far 35,000 women, including those from under represented groups in breast cancer research such as African-American women, and military veterans, have joined. (Marc and Lynne Benioff, the co-chairs and owners of TIME, have been philanthropic supporters of Dr. Esserman’s breast cancer research. The WISDOM study receives software support from Salesforce, where Marc Benioff is chairman and CEO.)


In a series of short videos for Breast Cancer Awareness Month this October, we will meet several women who are participating in WISDOM, and explore what they’ve learned about their own risk for breast cancer, and how the knowledge they’ve gained has changed the way they think about the disease, from a woman who thought she was at high risk because of a family history of breast cancer, but turned out not to need the intensive screening she was getting, to a woman whose genes were hiding a predisposition for the disease she never would have otherwise learned, to African-American women at higher risk of a more aggressive form of the cancer.

[**_Bookmark this page_**](http://time.com/6102552/wisdom-breast-cancer-study-participants) **_and return to it throughout the month to see the videos as we release them._**

* Oct. 4: [Meet the Women Participating in the Study That Could Change Future of Breast Cancer](https://time.com/6102552/wisdom-breast-cancer-study-participants/)
* Oct. 13: [Why a One-Size-Fits-All Approach to Breast Cancer Prevention Can Leave Women Vulnerable](https://time.com/6102568/breast-cancer-screenings-wisdom-study/)

```json
[{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/6102552/wisdom-breast-cancer-study-participants/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/6102552/wisdom-breast-cancer-study-participants/"},"headline":"Meet the Women Participating in the Study That Could Change Future of Breast Cancer","datePublished":"2021-10-04T20:10:33.000Z","dateModified":"2026-02-24T10:21:45.531Z","description":"When it comes to breast cancer, the sobering truth is that despite all the advances in new treatments, doctors still aren’t very good selecting out the women at the highest risk","url":"https://time.com/6102552/wisdom-breast-cancer-study-participants/","keywords":["Cancer","healthscienceclimate"],"thumbnailUrl":"https://static.time.com/v3/assets/bltea6093859af6183b/blt5a2275fcc368a3b0/698a1d7bb21a9c2f54505373/esserman_thumb_v02.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","author":[{"@type":"Person","name":"Alice Park","jobTitle":"Senior Correspondent","url":"https://time.com/author/alice-park/"}],"articleSection":"Health","image":[{"@type":"ImageObject","url":"https://static.time.com/v3/assets/bltea6093859af6183b/blt5a2275fcc368a3b0/698a1d7bb21a9c2f54505373/esserman_thumb_v02.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","width":1200,"height":675,"headline":"Dr. Laura Esserman","caption":"Dr. Laura Esserman, UCSF Breast Surgeon and Oncologist, Founder of the Wisdom Study","creditText":"Vatsala Goel for Time","representativeOfPage":true}],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/health/","name":"Health"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/cancer/","name":"Cancer"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/6102552/wisdom-breast-cancer-study-participants/","name":"Meet the Women Participating in the Study That Could Change Future of Breast Cancer"}}]}]
```

