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---
title: Google DeepMind Announces World-Leading AlphaFold 3 Model
description: The innovative AI model, announced on May 8, is likely to dramatically accelerate biological research.
canonical: https://time.com/6975934/google-deepmind-alphafold-3-ai/
author: Will Henshall
article:opinion: false
article:content_tier: free
article:published_time: 2024-05-08T15:00:00.000Z
article:modified_time: 2026-04-13T08:53:20.665Z
article:section: Business
og:title: Google DeepMind’s AlphaFold 3 Could Transform Drug Discovery
og:description: The innovative AI model, announced on May 8, is likely to dramatically accelerate biological research.
og:url: https://time.com/6975934/google-deepmind-alphafold-3-ai/
og:site_name: TIME
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og:image:width: 1200
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og:image:alt: Credit-Google-DeepMind_AF3-blog-hero.png
og:type: article
twitter:card: summary_large_image
twitter:title: Google DeepMind’s AlphaFold 3 Could Transform Drug Discovery
twitter:description: The innovative AI model, announced on May 8, is likely to dramatically accelerate biological research.
twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt19ce23c0f1b77878/698a5687cabb1d414be541a4/Credit-Google-DeepMind_AF3-blog-hero.png?branch=production&amp;width=3840&amp;quality=75&amp;auto=webp&amp;crop=16:9
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# Google DeepMind’s Latest AI Model Is Poised to Revolutionize Drug Discovery

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## Video: The 3 Most Important AI Innovations of 2023

[Watch (HLS stream): The 3 Most Important AI Innovations of 2023](https://cdn.jwplayer.com/manifests/gIt8zUdS.m3u8) (4:14)

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_Published 2023-12-20. In many ways, 2023 was the year that people began to understand what AI really is—and what it can do. Here are three of the biggest AI innovations from the past year._


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## Will Henshall


May 8, 2024 3:00 PM CUT

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Courtesy Google DeepMind

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## Will Henshall


May 8, 2024 3:00 PM CUT

Researchers at Google DeepMind have developed AlphaFold 3, an AI model that can predict the structure of and interactions between biological molecules including proteins, DNA and RNA, and small molecules that could function as drugs. Google DeepMind will make the model available for non-commercial use through [AlphaFold server](http://alphafoldserver.com "undefined"). The landmark innovation, the details of which were published in the journal _Nature_ on May 8, is likely to dramatically accelerate biological research. 

“It's a big milestone for us today, announcing AlphaFold 3,” said Demis Hassabis, CEO of Google DeepMind, at a briefing on May 7 announcing the breakthrough. “Biology is a dynamic system and you have to understand how properties of biology emerge through the interactions between different molecules in the cell. You can think of AlphaFold 3 as our first big step towards that.”

The AI system is a descendant of [previous AlphaFold models](https://time.com/collection/best-inventions-2022/6229912/deepmind-alphafold/ "undefined") built by Google DeepMind that essentially [solved](https://time.com/6201423/deepmind-alphafold-proteins/ "undefined") the problem of predicting the three-dimensional structure of a protein from its amino acid structure. Google DeepMind’s first AlphaFold model, announced in 2018, attempted to predict protein structures, coming first in an international protein structure prediction competition. AlphaFold 2, released in 2020, significantly improved on the first’s protein structure accuracy predictions. 

AlphaFold 3 goes further by predicting the structures of almost all biological molecules and modeling the interactions between those molecules. While researchers have long developed specialized computational methods for modeling interactions between specific types of biological molecules, AlphaFold 3 marks the first time that a single system has been able to predict the interactions between nearly all molecular types with state-of-the-art performance.

### More From TIME

The properties and functions of molecules in biological systems are typically a result of how they interact with other molecules. Using experiments to understand molecular interactions can take years of research time and be prohibitively expensive. If these interactions can instead be estimated computationally with sufficient accuracy, then biological research can be dramatically accelerated. For example, if researchers believe that a molecule that binds to a specific site on a certain protein would be a promising drug candidate, they can use computational systems such as AlphaFold 3 to test potential drug molecules.


“AlphaFold continues to get better, and increasingly more relevant for biological investigations,” said Paul Nurse, the Nobel Prize-winning geneticist and chief executive and director of the London-based biomedical research center the Francis Crick Institute, in a statement accompanying the Google DeepMind announcement. “This third version will enable increased accuracy in predicting the structures of complexes between different macromolecules, as well as associations between macromolecules, small molecules and ions.”

Google DeepMind was founded as DeepMind in 2010 by Hassabis, along with Google DeepMind Chief AGI Scientist [Shane Legg](https://time.com/collection/time100-ai/6310659/shane-legg/ "undefined") and [Mustafa Suleyman](https://time.com/collection/time100-ai/6309466/mustafa-suleyman/ "undefined"). (Suleyman is now CEO at Microsoft AI, Microsoft’s consumer AI products and research organization.) DeepMindwas acquired by Google in 2014, and in 2023 Google merged DeepMind with Google Brain, another Google AI division, to form Google DeepMind, putting an end to [efforts](https://www.wsj.com/articles/google-unit-deepmind-triedand-failedto-win-ai-autonomy-from-parent-11621592951 "undefined") by DeepMind’s leadership to secure greater autonomy from their parent company.


In addition to the AlphaFold family of AI systems, Google DeepMind has made several breakthroughs that use AI to further science and technology. In 2022 the company [released](https://deepmind.google/discover/blog/discovering-novel-algorithms-with-alphatensor/ "undefined") an AI system that can discover novel algorithms, and in 2023 it [released](https://deepmind.google/discover/blog/graphcast-ai-model-for-faster-and-more-accurate-global-weather-forecasting/ "undefined") an AI model that could forecast the weather with unprecedented accuracy. Also in 2023, Google DeepMind [released](https://time.com/6340681/deepmind-gnome-ai-materials/ "undefined") an AI model that it claims accurately predicts the structures of materials, although the utility of this model has since been [called into question](https://www.404media.co/google-says-it-discovered-millions-of-new-materials-with-ai-human-researchers/ "undefined") by independent researchers.

In 2021, Google parent company Alphabet [announced](https://www.isomorphiclabs.com/articles/introducing-isomorphic-labs "undefined") the creation of Isomorphic Labs, which aims to take an AI-first approach to drug discovery. Researchers from Isomorphic Labs contributed to the development of AlphaFold 3 and, while AlphaFold Server can be used by anyone from non-commercial research, researchers at Isomorphic Labs will have exclusive access to AlphaFold 3 for commercial use.


“We've been using AlphaFold 3’s capabilities day-to-day in our drug design programmes,” said Max Jaderberg, chief AI officer at Isomorphic labs, at the announcement briefing. “We're already seeing that potential to accelerate, improve, and ultimately transform the way that we do drug discovery, and it's really because of the new level of accuracy of this model, and the increased breadth of biomolecules that this model is able to predict, that really enables that for us.”

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