Over the past 10 years, TIME has chosen some of the world’s biggest movers and shakers for its annual list of the most influential people in the world. Many of them have continued to transform themselves and the lives of others long after their inclusion.
Take Hillary Clinton, for example. The one-time First Lady has appeared on the list eight times (including one time with husband Bill) as she evolved from senator to presidential candidate to Secretary of State to (unofficial) presidential candidate again. We’ve selected several other honorees that we think fit the bill.