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title: Risk Factors for Heart Disease and Predicting Heart Attacks
description: Of the five popular tools that doctors rely on to predict whether you’re headed for heart trouble, four of them have a pretty major flaw
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# Why Your Heart Disease Risk Might Be Lower Than You Think

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## Video: The Truth About Fat

[Watch (HLS stream): The Truth About Fat](https://cdn.jwplayer.com/manifests/uYGhfNfS.m3u8) (5:15)

![The Truth About Fat](https://cdn.jwplayer.com/v2/media/uYGhfNfS/poster.jpg?width=720)

_Published 2014-06-12. When you want to lose weight or get healthy, what is the first thing you would normally cut from your diet? If you said fat, you're not alone_


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Feb 18, 2015 5:00 PM UTC

![Stethoscope](https://static.time.com/v3/assets/bltea6093859af6183b/blt50d46bb040f2619b/69876da33c1639b2b3450873/doctor.jpg?branch=production&width=1200&quality=75&auto=webp&crop=3:2)

Stethoscope

Stethoscope Getty Images

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by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Feb 18, 2015 5:00 PM UTC

For decades, doctors have relied on the undisputed champion of heart disease risk assessment: the Framingham Risk Score. It emerged from a massive study of heart disease risk factors in more than 5,000 men and women and pointed out advanced age, being male, smoking, having diabetes, high total cholesterol, low levels of good cholesterol and high blood pressure. Scoring higher on these factors meant you had a greater chance of developing heart problems in the next 10 years, and most successive models included some version of these core culprits.

Now, scientists led by Dr. Michael Blaha, director of clinical research at the Ciccarone Center for Prevention of Heart Disease at Johns Hopkins Medicine, have published a new [study](http://www.annals.org/article.aspx?doi=10.7326/M14-1281) in the _Annals of Internal Medicine_ that finds that those risk calculators—four of which doctors use regularly—tend to overestimate the risk of heart attack in patients.

**MORE:** [New Guidelines for Cholesterol Treatments Represent “Huge Change”](http://healthland.time.com/2013/11/12/new-guidelines-for-cholesterol-treatments-represent-huge-change/)

“It’s not that scientists made mistakes when coming up with the \[calculators\],” says Blaha, “They did the best job they could with the data they had. But there may be inherent problems in using historical data to predict things now.”

The diet and lifestyle of Americans have changed considerably since the Framingham days, when heart attacks occurred more frequently in younger people and more often in men than women. Americans on average now eat more trans fat and salt and have lower exposure to secondhand smoke, which can all affect heart disease rates.


**MORE:** [Cholesterol Whiplash: What to Make of the New Heart-Risk Calculator](http://healthland.time.com/2013/11/18/cholesterol-whiplash-what-to-make-of-the-new-heart-risk-calculator/)

But even the [most recent guidelines for predicting heart disease risk](http://healthland.time.com/2013/11/12/new-guidelines-for-cholesterol-treatments-represent-huge-change/), released in 2013 by the American Heart Association and the American College of Cardiology, relied on the Framingham Risk factors. In the current analysis, these guidelines overestimated heart attack risk by 86% in men and 67% in women when Blaha and his team compared the predicted risk to actual rates of heart events in a group of more than 4,000 people aged 50 to 74 years, who were followed up for an average of 10 years. The other models overshot the risk by anywhere from 37% to 154% for men, and from 8% to 67% for women.

That’s a lot of extra heart disease that, under current guidelines, doctors may start treating with blood pressure medications, insulin and cholesterol-lowering drugs. All of those come with potential side effects and complications. In fact, the study found that statins to keep cholesterol in check were least effective among those with the lowest risk of having future heart events, meaning the benefits may not outweigh the risks for many.


**MORE:** [Single Gene Responsible for Group of Heart Disease Risk Factors](http://time.com/99683/single-gene-responsible-for-group-of-heart-disease-risk-factors/)

“We’re getting close to the idea of re-thinking risk,” says Blaha. Instead of relying on decades-old data that draws conclusions and recommendations on a population level, ideally everyone’s risk should be more individualized and based on his own particular history. The Framingham model, for example, includes data collected from a single measurement of blood pressure and cholesterol, and a yes-or-no answer on whether the patient smokes. But someone who has smoked for years and just quit is physiologically different from someone who never lit up at all, just as having blood pressure that’s under control thanks to medication is not the same as never having hypertension to begin with. The most accurate way to predict someone’s risk of having a heart attack is to survey his blood pressure and cholesterol readings over his lifetime, or at least for many years. That may soon be possible with electronic health records and the popularity of medical monitoring bracelets. But until then, any model that relies on population-based data like Framingham may suffer from overestimating someone’s heart danger, Blaha says.


**MORE:** [Eating Fruit Cuts Heart Disease Risk by 40%](http://time.com/3263737/eating-fruits-cuts-heart-disease-risk/)

“These data point squarely to the idea that we need to be rethinking risk prediction,” he says. That may require not just combing through more data per patient, but also folding in other factors that may be more sensitive to the health of a person’s heart. Imaging techniques, including coronary calcium scores that measure the amount of calcium—a foundation for the plaques that eventually rupture to cause heart attacks—may provide more valuable and accurate information on a person’s risk, for example.

In the meantime, Blaha isn’t advocating for the elimination of current risk predictors or guidelines that help doctors decide when a patient’s risk warrants treatment with a drug. “The guidelines are still useful, but patients and doctors have to understand the caveats and limitations to them,” he says. Whatever score a patient receives from these calculators, that number should be the starting point of a discussion between doctor and patient about that patient’s particular risk factors—including his family history, whether and how much he smoked, and how much exercise he gets on a regular basis. “Patients need to demand, or ask their doctors to go beyond the number and say, ‘Do you really think I need to starting taking medicine?’ or ‘How much risk do I really have of having a heart attack?’” That kind of conversation is far more valuable than a single-risk calculator will ever be.



## Transcript

[ MUSIC ] There's something we all enjoy about staying for dinner. You ever thought why? What was on your dinner table when you were younger? Chances are it had a lot to do with, what your doctor was telling you is healthy. Building a strong healthy body is like building a strong, beautiful building. If the foundation is weak, the whole building will be weak. It takes five fingers to point the way to healthful eating habits. Well, here we go. For years, the government published dietary guidelines. Meant to keep Americans healthy. There's a great deal to learn. Tell me what you eat, and I'll tell you what you are.

The body needs certain substances to live and grow. And remember, your body isn't just like an automobile. For years, the key measures of those guidelines were the same, cut fat from your diet. The committee's original report urged Americans to reduce their risk of heart attack. By reducing their intake of cholesterol down to the equivalent of about one egg a day. And those guidelines had an effect. From 1977 to 2012, per capita consumption of eggs fell by 9 %, beef by 37 %, whole milk by 72 %. Calories from saturated fat fell, while calories from supposedly safe carbohydrates increased. As one expert put it, it was a vast nutritional experiment.

With nearly a million American's a year dropping dead from heart disease in the mid 80s, we had to try something. Nearly four decades later results are in. The experiment was a failure. Americans are sicker than they've ever been before. The prevalence of diabetes has gone up 157 % from 1980 to 2011. Nearly one in ten Americans now has the disease. Causing the public health system $ 245 billion a year. Heart disease is still the number one killer in the country. Americans are as obese as ever. So, what went wrong? Good old granola. Great for taste but loaded with fat. It doesn't take much of imagine a leap to assume that fat would make us fat, clog our arteries and raise the risk of heart disease.

It turns out that saturated fat is a lot more complicated than we think. Carbohydrates and fats are nutrients. Like man, you need nutrients to live and grow. [ MUSIC ] Firstly, there are two kinds of cholesterol. LDL which is linked to heart disease and HDL which can be protective. Fats that course through the blood are known as triglycerides and high levels of those are linked to heart disease. Saturated fat raises LDL cholesterol but also raises HDL. Moving LDL buildup on arterial walls. So raising both, makes saturated fat a cardio wash. One key piece of information is that LDL seems to come in two forms.

Large and fluffy, small and dense. Those smaller particles are linked to heart disease, while the larger ones are mostly benign. Saturated fat increases the number of large particles. The opposite happens with carbs. I don't get it. Researchers have long since discovered the kind of fats found in olives and in fish like salmon. Are actually heart protective. Now it turns out the fats found in meat and dairy, aren't as bad as we feared before. So that means by focusing so much on fats. We may actually have been making ourselves sicker. So, she brings up the subject of reduced- fat cheese. It's a fat- free [ UNKNOWN ].

Fat- free, cholesterol free. Low- fat granola. Reduced- fat Kettle chips. Reduced- fat Chips Ahoy. Lowfat cottage cheese. Non- fat yogurt is the perfect example. The thinking for consumers was simple. Fat was dangerous. This product had no fat. Therefore, it must be healthy. It's non- fat, which means less calories. [ MUSIC ] But amid the confusion about fat, we end up replacing it in our diets with sugars and carbohydrates, which meant our calorie intake was actually going up. When carbs and things like corn and white bread are ingested into your body, their converted into sugars. Those sugars convert to insulin cuz it's fat cells go into storage overdrive, leading to weight gain.

Since fewer calories are then left to fill the body, you begin to feel hungry it means our metabolism begins to slow down in effort to save energy, we eat more and we gain more weight, never quite feeling full. As this process repeats, our cells become more resistant to insulin, which causes us to gain more weight, which increases insulin resistance in a vicious circle. Cut calories, and people just get hungrier. Obesity, diabetes, high triglycerides and low HDL cholesterol can all follow. Study after study has found it's very difficult to lose weight on a very low- fat diet. Possibly because fat and meat can produce a sense of satiety, that's hard to achieve with carbs, making it easier to simply stop eating.

But it isn't just the increase in carbs that affects us. These processed, low saturated fat alternatives, come loaded with sugars, salt, preservatives, and even some unhealthy fats. So what's the real alternative? As one extra puts it, the cold hard truth about diet is that the only way to eat well, is to eat well. You'll be happier and you'll be healthier, if you focus on real whole foods, whether they have fat or not. Got it. And thanks, we'll never forget what we've learned.

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