--- description: Find out why Colossal Biosciences was selected for the list title: TIME100 Most Influential Companies 2023: Colossal Biosciences image: https://static.time.com/v3/assets/bltea6093859af6183b/blt43d9d279c4ed42c0/698a3dc3d07533dc48e6e1b9/time100-companies-Colossal-Biosciences-2023.jpg?branch=production&width=3840&quality=75&auto=webp&crop=16:9 --- Jun 21, 2023 # Colossal Biosciences Reversing extinction by [Jeffrey Kluger](/author/jeffrey-kluger/) ## Jeffrey Kluger Update your preferences in [Account Settings](/account/preferences/) Close Editor at Large  A visualization of a woolly mammoth, which Colossal Biosciences aims to "de-extinct." A visualization of a woolly mammoth, which Colossal Biosciences aims to "de-extinct."Courtesy of Colossal Biosciences It’s been 4,000 years since the woolly mammoth went extinct, but Dallas-based Colossal Biosciences wants to change that. In 2022, it announced it had sequenced the genome of the Asian elephant, which shares 99.6% of its genes with the woolly mammoth. Combining that with DNA samples from mammoth remains could mean a rebirth of the species. The company hopes to work its “de-[extinction](https://time.com/6275373/giant-yangtze-softshell-turtle-female-dies/ "undefined")” magic on other species, including the dodo and the Tasmanian tiger, and threatened species could be saved from extinction by editing more diversity into their genomes, making them more robust. _A weekly newsletter featuring conversations with the world’s top CEOs, managers, and founders._ [_Join the Leadership Brief_](https://cloud.newsletters.time.com/signup?nln=leadership&source=100companies "undefined"). Colossal Biosciences: 2023 TIME100 Most Influential Companies ```json [{"@context":"https://schema.org","@type":"Article","@id":"https://time.com/collections/time100-companies-2023/6285144/colossal-biosciences-2/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/collections/time100-companies-2023/6285144/colossal-biosciences-2/"},"headline":"Most Influential Companies 2023: Colossal Biosciences","datePublished":"2023-06-21T10:55:40.000Z","dateModified":"2026-03-03T00:15:35.395Z","description":"","url":"https://time.com/collections/time100-companies-2023/6285144/colossal-biosciences-2/","keywords":["TIME100 Companies"],"thumbnailUrl":"https://static.time.com/v3/assets/bltea6093859af6183b/blt43d9d279c4ed42c0/698a3dc3d07533dc48e6e1b9/time100-companies-Colossal-Biosciences-2023.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","author":[{"@type":"Person","name":"Jeffrey Kluger","jobTitle":"Editor at Large","url":"https://time.com/author/jeffrey-kluger/"}],"creator":"Jeffrey Kluger","articleSection":"","image":[{"@type":"ImageObject","url":"https://static.time.com/v3/assets/bltea6093859af6183b/blt43d9d279c4ed42c0/698a3dc3d07533dc48e6e1b9/time100-companies-Colossal-Biosciences-2023.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","width":1200,"height":675}],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https://time.com/collections/time100-companies-2023/6285144/colossal-biosciences-2/","name":"Most Influential Companies 2023: Colossal Biosciences"}}]}] ```