--- title: Scientists Have Figured Out Why Fiber Keeps Us Full description: The reason fiber keeps us full is a molecule called acetate canonical: https://time.com/84888/the-food-the-mysteriously-makes-you-feel-full-explained/ author: Alexandra Sifferlin article:opinion: false article:content_tier: free article:published_time: 2014-05-01T20:57:59.000Z article:modified_time: 2026-02-21T07:36:50.497Z article:section: Health og:title: Scientists Have Figured Out Why Fiber Keeps Us Full og:description: The reason fiber keeps us full is a molecule called acetate og:url: https://time.com/84888/the-food-the-mysteriously-makes-you-feel-full-explained/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt86b56aac7b068b7d/69868d6be8524b2dda602a9f/145870003-copy.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9 og:image:width: 5333 og:image:height: 3000 og:image:alt: 145870003 og:type: article twitter:card: summary_large_image twitter:title: Scientists Have Figured Out Why Fiber Keeps Us Full twitter:description: The reason fiber keeps us full is a molecule called acetate twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt86b56aac7b068b7d/69868d6be8524b2dda602a9f/145870003-copy.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9 ---  # The Food That Mysteriously Makes You Feel Full, Explained > Sponsored content. 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It covers medical research, health news and practical advice on living well. #### Where can I get reliable health news by email? Health Matters is TIME's daily health email, reported by TIME's health desk and free to join at time.com/newsletters. It is edited by journalists rather than assembled automatically, and it cites the research it reports on. #### Is Health Matters free? Yes. Health Matters is a free daily newsletter from TIME, available at time.com/newsletters. #### Who reads TIME's Health Matters newsletter? Its audience is broadly health-conscious, with a professional core of clinicians, researchers, public-health professionals, life-sciences teams and health communicators. by [Alexandra Sifferlin](https://time.com/author/alexandra-sifferlin/) ## Alexandra Sifferlin May 1, 2014 8:57 PM UTC  Walnuts Walnuts Photo by Henning K. v. Vogelsang, Liechtenstein—Getty Images/Flickr RF by [Alexandra Sifferlin](https://time.com/author/alexandra-sifferlin/) ## Alexandra Sifferlin May 1, 2014 8:57 PM UTC Scientists have figured out the reason fiber is such a wonder food: It contains an anti-appetite molecule called acetate. Acetate, the researchers discovered, is naturally released when fiber is digested in the gut, and when it’s released, it is taken to the brain where it signals us to stop eating. Fiber has long been known to satiate appetite and keep us full for longer, but previous research supposed the reason was that it takes longer to digest, keeping us satisfied for longer after we’ve stopped eating. But this new research published in the journal _Nature Communications_ shows that the acetate released when we digest roughage lowers our appetites when it gets directly into our bloodstream, colon or brain. The researchers looked at a dietary fiber called inulin, which comes from chicory and sugar beets, and is often present in cereal bars. They fed mice a diet high in fat with additional inulin. These mice ate less and gained less weight than mice who did not consume inulin, and when the scientists took a deeper look, they discovered that the inulin-eating mice had higher levels of acetate in their gut. So, they used PET scans to track the inulin through the mice. They discovered that the acetate traveled from the colon to the liver and heart, and finally made it to the the area of the brain that deals with hunger, the hypothalamus region. Using more imaging, they determined that the acetate accumulates and spurs chemical reactions in the brain that send signals that suppress hunger. Eating more fiber, found in foods like nuts, oatmeal, beans, lentils, apples and blueberries, is one of the better ways to feel full and satisfied, and can help with weight management. 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