April 24, 2014 7:00 AM EDT

The 2014 TIME 100 list–the annual determination of people who influenced the world in the past year for better or worse–is here, and we highlight the leaders making a difference in health.

This year, TIME recognizes innovators who tackled issues from hunger and maternal health to marijuana and aging.

  • Christy Turlington Burns, an ambassador for maternal health. Burns founded Every Mother Counts, which provides poor countries with health education, medicine and emergency care.
  • Ertharin Cousin, a Chicagoan who helps feed the world. As head of the U.N.’s World Food Program, Cousin is responsible for feeding over 100 million people each year.
  • Aliko Dangote, doing well and doing good for Africa. Dangote is one of the richest men in Africa who also dedicates his time to ridding countries of infectious diseases.
  • Robert Lanza, in the vanguard of stem-cell research. Dr. Lanza is the chief scientific officer at the biotech firm Advanced Cell Technology, and found a way to turn adult cells into stem cells that may soon be turned into new treatments, or cures, for diseases like diabetes and Alzheimer’s.
  • José Mujica, the revolutionary who legalized pot. As Uruguay’s president, José “Pepe” Mujica signed a law making the country the first to legalize the production and sale of marijuana.
  • Arunachalam Muruganantham, an unlikely health crusader. Muruganantham designed a simple machine to make sanitary napkins after seeing how hard it was for his wife to get access to affordable ones.
  • David Sinclair, bringing us closer to reversing aging. Sinclair is a genetics professor at Harvard Medical School who discovered a compound that makes old cells act young again.
  • Alice Waters, pioneer of good food for all. As a respected chef, Waters promotes accessible produce for everyone, including for the youngest eaters, with the Edible Schoolyard Project.

Contact us at editors@time.com.

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