Updated: September 25, 2022 8:47 PM EDT | Originally published: March 25, 2022 12:17 PM EDT

What began as a list of the world’s most influential people is now an expansive community of global change-makers.

Across every industry, TIME100 leaders—scientists and CEOs, artists and activists, pop stars and politicians—are moving our world forward. Just as TIME’s annual list recognizes achievement in one year, we also know influence endures. The TIME100 Impact Awards—which debuted in spring 2022 in Dubai, and will reconvene October 2022 in Singapore—recognize leaders who, through sustained effort, have done extraordinary work to shape the future of their industries and the world at large.

This fall’s honorees range from an iconic actor whose performances are receiving praise all across the globe to a visionary innovator who is helping humanity see further into the universe than before.

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