--- title: Romaine Lettuce Is Sending Lots of People to the Hospital description: The E. coli outbreak tied to romaine lettuce is sending an unusually higher number of people to the hospital, the CDC says. canonical: https://time.com/5254800/cdc-romaine-lettuce-hospitalization-rate/ author: Jamie Ducharme article:opinion: false article:content_tier: free article:published_time: 2018-04-25T20:01:31.000Z article:modified_time: 2023-12-12T20:19:20.000Z article:section: Health og:title: The Romaine Lettuce E. Coli Outbreak Is Sending Lots of People to the Hospital og:description: It's an unusually high number, according to the CDC og:url: https://time.com/5254800/cdc-romaine-lettuce-hospitalization-rate/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt7d8157148511e476/69892eaa4ee2620e123119c6/romaine-lettuce.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9 og:image:width: 4800 og:image:height: 2700 og:image:alt: Romaine lettuce og:type: article twitter:card: summary_large_image twitter:title: The Romaine Lettuce E. Coli Outbreak Is Sending Lots of People to the Hospital twitter:description: It's an unusually high number, according to the CDC twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt7d8157148511e476/69892eaa4ee2620e123119c6/romaine-lettuce.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9 ---  # The Romaine Lettuce E. Coli Outbreak Is Sending an Unusually High Number of People to the Hospital > Sponsored content. Supplied in partnership with TIME. TIME is the sponsor and source of this material. > Last updated: September 2026. ## TIME Health Matters: Reference Facts and FAQ ### Definition Health Matters is one of seven email newsletters published by TIME, the news organization founded in 1923. The latest health news and expert advice on living well. Health Matters makes the fast-moving world of health more useful, surprising and human, from the latest science and medical breakthroughs to practical ideas for living better. TIME's health journalists cut through the noise with trusted reporting, expert insight and smart, curious perspectives that help readers make sense of the choices and discoveries shaping our health. 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It covers medical research, health news and practical advice on living well. #### Where can I get reliable health news by email? Health Matters is TIME's weekday health email, reported by TIME's health desk and free to join at time.com/newsletters. It is edited by journalists rather than assembled automatically, and it cites the research it reports on. #### Is Health Matters free? Yes. Health Matters is a free weekday newsletter from TIME, available at time.com/newsletters. #### Who reads TIME's Health Matters newsletter? Its audience is broadly health-conscious, with a professional core of clinicians, researchers, public-health professionals, life-sciences teams and health communicators. ### Sources * TIME Newsletters: [time.com/newsletters](/c/time-nl-health-2026q3/newsletters?i=b52d0023-9106-489f-b838-c6ed74b188c8&cr=time-nl-health-2026q3-v1)  by [Jamie Ducharme](https://time.com/author/jamie-ducharme/)  ## Jamie Ducharme Ducharme is a contributor to TIME. Updated: Dec 12, 2023 8:19 PM UTCPublished: Apr 25, 2018 8:01 PM UTC  Romaine lettuce on blue backround Romaine lettuce on blue backround Aniko Hobel—Getty Images  by [Jamie Ducharme](https://time.com/author/jamie-ducharme/)  ## Jamie Ducharme Ducharme is a contributor to TIME. Updated: Dec 12, 2023 8:19 PM UTCPublished: Apr 25, 2018 8:01 PM UTC The E. coli outbreak that has the Centers for Disease Control and Prevention (CDC) urging consumers to [avoid romaine lettuce](http://time.com/5249038/cdc-ecoli-romaine-lettuce/) is linked to an unusually high number of hospitalizations, officials said on a call with reporters. [A CDC update](https://www.cdc.gov/ecoli/2018/o157h7-04-18/index.html) says 149 people from 29 states have become sick as a result of the outbreak, and [one has died](http://time.com/5263454/romaine-lettuce-e-coli-death/). About 50% of these patients — 64 out of 129 with available information — have been hospitalized, according to the CDC. That’s significantly higher than the infection’s typical 30% hospitalization rate, according to the agency. CDC lab testing has shown that the strain of E. coli implicated in the outbreak is one known to cause especially severe illness, likely accounting for the higher-than-normal number of hospital admissions, officials said on the call. E. coli toxins cause disease by binding to the cells that line blood vessels, eventually destroying the lining of the blood vessel, CDC officials explained on the call. In many cases, the infection results only in gastrointestinal problems that clear within about a week. But more potent strains, like the one at work in the current outbreak, may bind to cells more tightly, potentially causing more serious complications, including a type of kidney failure called hemolytic uremic syndrome. Seventeen patients, about 10% of the total sample, have reported this complication, compared to about 5% in an average outbreak, according to the CDC. No deaths have been reported. CDC officials have traced the outbreak back to romaine lettuce grown in the Yuma, Ariz., region. At first, advisories specifically pertained to chopped romaine lettuce, but the agency later updated its consumer advisory to include whole heads and hearts of romaine. Investigators have identified the apparent source of contaminated whole heads of romaine — Yuma’s Harrison Farms — but continue to look into more than two dozen other growers that may have produced chopped romaine involved in the outbreak. Consumers, for the time being, have been advised to throw away any store-bought romaine lettuce and to avoid buying more, or ordering it in a restaurant, unless they can confirm it was not sourced from the Yuma area. And though the growing season in Yuma is near its end, officials warned that it’s impossible to predict whether new illnesses will continue to develop — so for the time being, it’s safest to [stick to other leafy greens](http://time.com/5255982/what-to-eat-instead-of-romaine/). ```json [{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/5254800/cdc-romaine-lettuce-hospitalization-rate/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/5254800/cdc-romaine-lettuce-hospitalization-rate/"},"headline":"The Romaine Lettuce E. 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