QUEEN ELIZABETH II
1952
Settling into the throne
NOW
Setting a new record Sept. 9 as the longest-reigning British monarch; she’s nearing 64 years
BILL CLINTON
1992, 1998
Elected as the first baby-boomer U.S. President; then trying to hold on in the face of impeachment
NOW
Potentially ready to bring new meaning to “First Spouse” if his wife becomes President
JEFF BEZOS
1999
Leading Amazon.com, the company he founded, to usher in an era of e-commerce
NOW
Taking Amazon into everything from devices to drones–and pursuing his own commercial space venture
VLADIMIR PUTIN
2007
Rebuilding Russia as a world power
NOW
Making military moves in Ukraine, Syria and more–and butting heads with the U.S.
BARACK OBAMA
2008, 2012
Getting elected (and re-elected) as America’s first black President, promising hope and change
NOW
Preparing to leave office with a legacy of health care reform–but also renewed national-security concerns
MARK ZUCKERBERG
2010
Driving the social-networking phenomenon with 550 million Facebook users
NOW
Becoming a dad and expanding philanthropic efforts, all while reaching 1.55 billion active monthly users
THE PROTESTER
2011
Demanding justice and dignity in over a dozen countries during the Arab Spring revolutions
NOW
Other than in Tunisia, finding their efforts have largely soured–especially in Egypt and Syria
POPE FRANCIS
2013
Inspiring a new generation of believers and nonbelievers to see the church in a friendlier light
NOW
Confronting conservative elements in the church with (relatively) progressive stances on key issues
THE EBOLA FIGHTERS
2014
Working to stop a deadly and frightening epidemic
NOW
Still working–but having made tremendous progress in halting the disease in West Africa
More Must-Reads from TIME
- Donald Trump Is TIME's 2024 Person of the Year
- Why We Chose Trump as Person of the Year
- Is Intermittent Fasting Good or Bad for You?
- The 100 Must-Read Books of 2024
- The 20 Best Christmas TV Episodes
- Column: If Optimism Feels Ridiculous Now, Try Hope
- The Future of Climate Action Is Trade Policy
- Merle Bombardieri Is Helping People Make the Baby Decision
Write to Lily Rothman at lily.rothman@time.com