31 Famous Friends Cameos

Friends
Brad Pitt – While he was still married to Jennifer Anniston, Brad Pitt played Ross' old high school friend who hated RachelNBC/Getty Images
George Clooney & Noah Wyle Guest On 'Friends'
George Clooney – Spoofing his E.R. fame, Clooney plays a dreamy doctor who takes care of Rachel's sprained ankleNBC/Getty Images
Friends - Season 2
Adam Goldberg – After Joey moved out, Adam Goldberg played Eddie, Chandler's creepy roommateNBC/Getty Images
Friends
Aisha Tyler – The Archer star played Charlie, a paleontologist who first dates Joey and then RossNBC/Getty Images
Friends
Alec Baldwin – Alec Baldwin guest-starred as Pheobe's way-too-enthusiastic dateNBC/Getty Images
Friends
Anna Faris – Anna Faris had a season-long role as Erica, whose twins Chandler and Monica adoptNBC/Getty Images
Friends
Ben Stiller – Ben Stiller appeared as Rachel's date who angrily yells at everyoneNBC/Getty Images
Friends
Billy Crystal – Crystal plays one of two crazy strangers (with Robin Williams) whose conversation the friends overhear at Central PerkNBC/Getty Images
Friends
Robin Williams – Williams plays that other crazy guy in Central PerkNBC/Getty Images
Friends
Brooke Shields – Joey ends up regretting going on a date with his crazy stalker played by Brooke ShieldsNBC/Getty Images
Friends
Bruce Willis – Things get complicated when Rachel starts dating Paul Stevens (Bruce Willis), the father of a student Ross is datingNBC/Getty Images
Friends
Christine Taylor – Rachel convinces Christine Taylor's Bonnie to shave her head so that Ross will break up with herNBC/Getty Images
Friends
Christina Applegate – Along with Reese Witherspoon, Christina Applegate played one of Rachel's spoiled sistersNBC/Getty Images
Friends
Dermont Mulroney – Gavin, played by Dermot Mulroney, fills in for Rachel while she's on maternity leave and later becomes a love interestNBC/Getty Images
Friends - Season 2
Charlie Sheen – When Charlie Sheen's Navy man visits Phoebe for an erotic weekend, they both come down with chicken poxNBC/Getty Images
Friends
Charlton Heston – Charlton Heston plays himself and gives Joey some acting adviceNBC/Getty Images
Friends
Dakota Fanning – Dakota Fanning offers Joey some advice on how to handle Chandler and Monica moving out of ManhattanNBC/Getty Images
Friends
Danny DeVito – Danny DeVito plays a stripper at Phoebe's bachelorette partyNBC/Getty Images
Friends
Freddie Prinze Jr. - Freddie Prinze Jr. is perfect as a sensitive male nanny who takes care of Ross and Rachel's daughterNBC/Getty Images
Friends
Helen Hunt – In a confusing crossover, Hunt (a Mad About You star) mistakes Phoebe for her twin sister Ursula (a real character played by Lisa Kudrow in both Friends and Mad About You)NBC/Getty Images
Friends
Hugh Laurie – The stranger sitting next to Rachel on her flight to England (Hugh Laurie) mocks her plan to break up Ross' weddingNBC/Getty Images
Friends - Season 1
Jay Leno – Leno plays himself interviewing Chandler's mom, an erotic novelist, on The Tonight ShowNBC/Getty Images
Friends
Jon Favreau – Jon Favreau spent almost a whole season as Monica's super-rich boyfriend who wants to become an Ultimate Fighting ChampionNBC/Getty Images
Friends - Season 1
Jon Lovitz – Jon Lovitz guest-starred as a restauranteur in season one and a blind date for Rachel in season 9NBC/Getty Images
Actor Matthew Perry and actress Julia Roberts
Julia Roberts – Julia Roberts plays "Susie Underpants," a girl whose skirt Chandler pulled down on stage in elementary schoolNBC/Getty Images
Friends
Kristin Davis – The Sex and the City star is befriended by Rachel and Phoebe after she starts dating JoeyNBC/Getty Images
Friends
Reese Witherspoon – Reese Witherspoon guest-stars as Rachel's younger sister who goes on a date with RossNBC/Getty Images
Friends
Sean Penn – Phoebe must tell her twin sister Ursula's fiancée, played by Sean Penn, that Ursula has been lying to him about her pastNBC/Getty Images
Friends
Susan Sarandon – In a plot line on Days of Our Lives, Joey gets Susan Sarandon's character's brainNBC/Getty Images
Friends
Tate Donovan – Real–life couple Jennifer Anniston and Tate Donovan played a couple on the show, tooNBC/Getty Images
Friends - Season 2
Tom Selleck – Tom Selleck's mustachioed Dr. Richard Burke dates Monica on-and-off for several seasonsNBC/Getty Images

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Write to Eliana Dockterman at eliana.dockterman@time.com