By Jennifer Latson
December 5, 2014

The 18th Amendment, which prohibited the production, distribution and sale of alcohol, easily ranks as the least popular amendment in U.S. history — and the only constitutional amendment ever to be repealed.

When the 21st Amendment was ratified on this day, Dec. 5, in 1933, it ended Prohibition 13 years, 10 months, and 19 days after it began. The time had not passed quickly, according to journalist H.L. Mencken, who noted, “It seems almost a geologic epoch while it was going on, and the human suffering that it entailed must have been a fair match for that of the Black Death or the Thirty Years War.”

The national experiment was a resounding failure, even according to some of its early supporters. Lifelong teetotaler John D. Rockefeller, Jr, had recanted his support the year before Prohibition’s repeal, in a letter published in the New York Times. He wrote:

While a Dallas newspaper editorial warned that Rockefeller’s change of heart “may in later years cause him deep regret,” William Randolph Hearst countered that Rockefeller’s opinion would help “bring the nation to calm conviction on the ineffectiveness of prohibition as a temperance measure.”

Early temperance advocates had warned that drunks were in danger — because of their high blood-alcohol levels — of spontaneous combustion (a claim that has since been proven impossible), but instead Prohibition sparked its own public health crisis. Drinking tainted bootleg liquor caused blindness, paralysis, and an estimated national average of 1,000 deaths a year.

Economically, the measure also failed to generate increased sales of clothing and household goods, which supporters claimed would skyrocket once breadwinners stopped throwing away their income in saloons. Sales of soda and juice were similarly expected to rise, along with entertainment industry revenue, as people sought ways to amuse themselves while sober. But those hopes were never realized; instead, the ban on alcohol cost the federal government $11 billion in lost tax revenue, according to Ken Burns’ documentary Prohibition.

President Franklin D. Roosevelt was among those relieved to witness the end of the era. “What America needs now is a drink,” he’s reported to have said.

Read a 1930 report on the 10th anniversary of Prohibition, here in the TIME Vault: Prohibition: Birthday

Photos: Prohibition and the Speakeasies of New York in 1933

Contact us at editors@time.com.

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