Angelina Jolie for Senate?

Angelina Jolie is “open” to running for office — though what office, exactly, is anyone’s guess.

Jolie, on the cover of Vanity Fair’s December issue, replied “I am open” when the magazine asked if she saw herself pursuing a career in politics, diplomacy, or public service.

“When you work as a humanitarian, you are conscious that politics have to be considered,” Jolie said. “Because if you really want to make an extreme change, then you have a responsibility.”

However, the actress — currently a Special Envoy of U.N. High Commissioner for Refugees António Guterres — added that her Hollywood commitments could “make it less possible.”

Jolie also talked to the magazine about Brad Pitt and her career. The issue is on newsstands on Nov. 11.

Read more at Vanity Fair.