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# Medical Momentum


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=3840&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Oct 16, 2014 10:53 AM UTC

![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=3840&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Oct 16, 2014 10:53 AM UTC

Progress in medicine can be an inch-by-inch slog. But every so often, small steps culminate in big advances. Such was the case in October, when researchers revealed game-changing discoveries that fundamentally alter their understanding of common but tough-to-treat conditions. These medical breakthroughs could pave the way for treatments that may someday be yours.

\[This article contains a table. Please see your hard copy of magazine or PDF.\]

| THE CONDITION           | THE BREAKTHROUGH                                                                                                                                        | THE PROMISE                                                                                                                                               | WHAT’S NEXT                                                                                                                                |
| ----------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------------------------ |
| ALZHEIMER’S             | Scientists call it “Alzheimer’s in a dish.” They can now see in a petri dish how the disease develops, a huge advance over animal models.               | Now that they can see what goes wrong with cells in the brain, experts can develop drugs that interfere with or stop the nerve-damaging disease.          | It’s the first step in a process that will likely take years before it produces a new therapy. But it’s a big step in the right direction. |
| AGE-RELATED VISION LOSS | Transplanting retinal cells grown from IVF embryos restored vision to people with macular degeneration– without any serious side effects.               | Half of the 18 patients can see three more lines on an eye chart, and some who were nearly blind can now see their watch and computer.                    | The study shows that these stem-cell transplants are safe, making it possible for more patients to participate in further trials.          |
| TYPE 1 DIABETES         | Researchers have created the first batch of insulin-making stem cells that respond to sugar both in a lab dish of human cells and in mice.              | If the cells are safe and effective for use in humans, they could effectively cure Type 1 diabetes and free patients from regular insulin injections.     | This kind of cure is years away. The cells must be tested for safety in humans and must be compared with existing treatments.              |
| C. DIFFICILE            | Fecal transplants can often cure this potentially lethal infection. Now scientists have a cleaner, less invasive vehicle: a pill.                       | Colonoscopies are replaced by capsules, which repopulate the patient’s gut with healthy, beneficial bacteria that wipe out the stubborn infection.        | The treatment is now available at a few clinics like Massachusetts General Hospital. Other medical centers are expected to follow.         |
| OBESITY                 | Scientists pinpointed a brain signal that turns abundant, unhealthy white fat into brown fat, which efficiently burns calories instead of storing them. | If a drug could turn this process on and off in a controlled way, it could help burn calories and reduce excess body fat, curbing obesity and overweight. | Brown-fat science, while exciting, is still in its early days. Stay tuned for news as the research develops.                               |

Sources: Nature; Lancet; Cell; JAMA

Medical Momentum

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