September 27, 2014 2:09 PM EDT
C helsea Clinton announced late Friday night that she gave birth to a healthy baby girl, Charlotte Clinton Mezvinsky. That makes Hillary Clinton a grandmother, and could have implications for her much-speculated 2016 presidential run—Clinton has said she wants to experience being a grandmother before deciding whether she’ll run for President.
Politics aside, the Twittersphere was aglow with will-wishing and congratulations for Chelsea Clinton on her daughter’s birth, with personalities from New York City Mayor Bill de Blasio to Democratic National Committee Vice Chairwoman Donna Brazile extending their regards.
Here are some of the choice tweets:
And here are some playful mentions thrown in for good measure:
Note the tongue-in-cheek cynicism, too:
Chelsea Clinton's Life in Pictures Gov. Bill Clinton, wife Hillary Rodham, and week-old baby Chelsea pose for a family picture, March 5, 1980. Donald R. Broyles—AP Arkansas Gov. Bill Clinton and daughter, Chelsea, 6, leave the voting booth after the governor cast his vote during the Democratic primary in Little Rock, Ark., on May 27, 1986. Danny Johnston—AP Arkansas Governor Bill Clinton is pictured here with his wife Hillary Rodham Clinton and their daughter Chelsea Clinton celebrating his inauguration as Governor in Little Rock, Ark. on Sept. 20, 1991. Danny Johnston—AP President Bill Clinton with daughter Chelsea, left and first lady Hillary Rodham Clinton wave to the crowd after taking the oath of office in Washington, Jan. 20, 1993. Ed Reinke—AP South African President Nelson Mandela and United States first lady Hillary Rodham Clinton, right, and daughter Chelsea Clinton, left, at a meeting in Cape Town, South Africa on March 20 1997. Doug Mills—AP President and Mrs. Clinton stand with their daughter, Chelsea, after her high school graduation ceremony at Sidwell Friends School in Washington on June 6, 1997. Sharon Farmer—AP President Clinton, daughter Chelsea and first lady Hillary Rodham Clinton walk with their Labrador "Buddy" to board Marine One for a two week vacation, just after President Clinton confessed to a relationship with former White House intern Monica Lewinsky, in Washington, Aug. 18, 1998. J. Scott Applewhite—AP Democratic presidential hopeful Sen. Hillary Rodham Clinton, D-N.Y., celebrates with her daughter Chelsea Clinton at her primary election night rally in Philadelphia on April 22, 2008. Carolyn Kaster—AP Chelsea Clinton and Marc Mezvinsky are seen during their wedding in Rhinebeck, N.Y. on July 31, 2010. Genevieve de Manio—AP National Day of Service Honorary Chair, Chelsea Clinton, left and Addison Rose, 8, of Washington, display the cards they made as part of the National Day of Service project on the National Mall in Washington, Jan. 19, 2013. Steve Helber—AP Chelsea Clinton, Special Correspondent for NBC News, takes part in the Education Nation Summit in New York City on Oct. 8, 2013. NBC/Getty Images Former President Bill Clinton and Vice Chair of the Board of the Clinton Foundation Chelsea Clinton meet with entrepreneurs during a visit to Coca-Cola's Clinton Global Initiative Commitment site at Park Station in Johannesburg, South Africa on Aug. 8, 2013. Jemal Countess—Getty Images Vice Chair of the Clinton Foundation Chelsea Clinton speaks during a student conference for the Clinton Global Initiative University, at Arizona State University in Tempe, Ariz. on March 22, 2014. Matt York—AP Chelsea Clinton, left, walks into her Oxford University graduation ceremony where she received her doctorate degree in international relations, at the Sheldonian Theatre in Oxford, England on May 10, 2014. Matt Dunham—AP Former President Bill Clinton, right, and former Secretary of State Hillary Rodham Clinton, second from right, wave to the media as Marc Mezvinsky and Chelsea Clinton pose for photographers with their newborn baby, Charlotte, after the family leaves Manhattan's Lenox Hill hospital in New York City on Sept. 29, 2014. William Regan—AP
More Must-Reads from TIME