“This represents a major advance in the identification of new treatments for age-related diseases such as diabetes”
Scientists have discovered a new hormone that mimics the health benefits of exercise by normalizing the metabolism and slowing the weight gain caused by fatty diets.
Appearing in the scientific journal Cell Metabolism on Tuesday, the study found the newly discovered MOTS-c hormone increases insulin sensitivity, allowing the body to more effectively process glucose sugars, according to a press release from the University of Southern California.
Insulin is a hormone that is used to move glucose sugars from food into the blood stream; resistance occurs when levels are high for a long period of time — commonly from a poor diet — which increases the body’s tolerance to the hormone and can lead to type 2 diabetes.
The new MOTS-c hormone targets muscle tissue and reverses age-dependent and diet-related insulin resistance.
“This represents a major advance in the identification of new treatments for age-related diseases such as diabetes,” said Dr. Pinchas Cohen, senior author of the study.
Researchers injected the new hormone into lab mice eating high-fat foods that usually lead them to become obese. The injection suppressed the weight gain and also reversed the insulin resistance caused by their diet.
While tests were only administered on mice, the necessary mechanisms are present in all mammals, humans included.