--- title: Why Inflammation Matters for Diabetics description: Anti-inflammatory medications might someday be used to lower the risk of certain kinds of disease among diabetics, found a new study presented at the American... canonical: https://time.com/3329225/inflammation-diabetes/ author: Mandy Oaklander article:opinion: false article:content_tier: free article:published_time: 2014-09-11T20:12:59.000Z article:modified_time: 2026-02-21T10:08:26.981Z article:section: Health og:title: Why Inflammation Matters for Diabetics og:description: Anti-inflammatory medications might someday be used to lower the risk of certain kinds of disease among diabetics, found a new study presented at the American... og:url: https://time.com/3329225/inflammation-diabetes/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production og:image:width: 1200 og:image:height: 675 og:image:alt: TIME og:type: article twitter:card: summary_large_image twitter:title: Why Inflammation Matters for Diabetics twitter:description: Anti-inflammatory medications might someday be used to lower the risk of certain kinds of disease among diabetics, found a new study presented at the American... twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production --- # Why Inflammation Matters for Diabetics > Sponsored content. 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Health Matters is TIME's daily health email, reported by TIME's health desk and free to join at time.com/newsletters. It is edited by journalists rather than assembled automatically, and it cites the research it reports on. #### Is Health Matters free? Yes. Health Matters is a free daily newsletter from TIME, available at time.com/newsletters. #### Who reads TIME's Health Matters newsletter? Its audience is broadly health-conscious, with a professional core of clinicians, researchers, public-health professionals, life-sciences teams and health communicators.  by [Mandy Oaklander](https://time.com/author/mandy-oaklander/)  ## Mandy Oaklander Oaklander is a senior editor at TIME. Sep 11, 2014 8:12 PM UTC  by [Mandy Oaklander](https://time.com/author/mandy-oaklander/)  ## Mandy Oaklander Oaklander is a senior editor at TIME. Sep 11, 2014 8:12 PM UTC Anti-inflammatory medications might someday be used to lower the risk of certain kinds of disease among diabetics, found a new [study](http://newsroom.heart.org/news/inflammation-may-be-key-to-diabetes-heart-disease-link?preview=e861) presented at the American Heart Association’s High Blood Pressure Research Scientific Sessions 2014. In the laboratory, the researchers studied cultured cells from a human aorta, the blood vessel that comes out of the heart and goes to the rest of the body. They put the cells in a high-glucose environment—similar to a what happens inside a diabetic body—and found that without inflammation present, sugar didn’t enter the cells. And even when glucose was forced into the cells, the cells weren’t damaged. But inflammation changes everything. When researchers added an inflammatory protein called interleukin-1—a common marker for inflammation in the body, whether you are diabetic or not—the cell _did_ metabolize the glucose, which kicked off a cycle of inflammation. Those effects were blocked once the researchers gave the cells a certain type of anti-inflammatory drug. “What \[the study authors\] said was, you need the inflammation in order for the glucose to do the damage to the cells,” explained Mary Ann Bauman, MD, a primary care internist at [INTEGRIS Health](http://integrisok.com/) in Oklahoma City and a spokesperson for the American Heart Association. (Dr. Bauman was not an author on the study.) “That could be one of the reasons why in a diabetic, if we can get them to exercise and lose weight, they will have less damage to their blood vessels.” In diabetes care, doctors and patients often focus on reducing blood sugar levels, and though this preliminary research occurred only in cells, it shows how inflammation might play a role, Dr. Bauman said. That means that controlling blood sugar isn’t always enough to avoid the cardiovascular disease that sometimes stems from diabetes, and anti-inflammatory drugs may one day be able to help, said study author Carlos Sánchez-Ferrer, professor of pharmacology at the Universidad Autónoma de Madrid in Spain, in a press release. Lifestyle changes can help, too. “We need to reduce the inflammatory environment associated with diabetes,” Sánchez-Ferrer said. “Changes in lifestyle, such as physical exercise and weight reduction, are important not only because they reduce blood sugar but because they reduce inflammation.” ```json [{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/3329225/inflammation-diabetes/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/3329225/inflammation-diabetes/"},"headline":"Why Inflammation Matters for Diabetics","datePublished":"2014-09-11T20:12:59.000Z","dateModified":"2026-02-21T10:08:26.981Z","description":"Anti-inflammatory medications might someday be used to lower the risk of certain kinds of disease among diabetics, found a new study presented at the American...","url":"https://time.com/3329225/inflammation-diabetes/","keywords":["diabetes","Heart Disease","type 2 diabetes","cardiovascular disease"],"thumbnailUrl":"","author":[{"@type":"Person","name":"Mandy Oaklander","jobTitle":"Oaklander is a senior editor at TIME.","url":"https://time.com/author/mandy-oaklander/"}],"articleSection":"Health","image":[],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/health/","name":"Health"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/diabetes/","name":"diabetes"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/3329225/inflammation-diabetes/","name":"Why Inflammation Matters for Diabetics"}}]}] ```