The San Francisco 49ers are hosting the Arizona Cardinals this week on Thursday Night Football.

The matchup is one of several games being live-streamed on Twitter for the first time this season. In partnership with Twitter, you can watch the game on SI.com or right here on Time.com.

The 49ers are 1-3, following a 24-17 loss to the Dallas Cowboys last week. The Cardinals are also 1-3, after falling to the Los Angeles Rams last week, 17-13.

The game is scheduled to kick-off at 8:25 p.m. E.T. Watch it live below.