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title: Two Scientists Honored with Nobel Prize in Medicine For Their Discovery of MicroRNA | TIME
description: Two scientists have been award the 2024 Nobel Prize in Physiology or Medicine for their discovery of microRNA. Victor Ambros, professor of molecular medicine at the University of Massachusetts Chan Medical School, and Gary Ruvkun, professor of genetics at Harvard Medical School and an investigator at Massachusetts General Hospital, received the prize for revealing how microRNAs turn genes on and off. 
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og:description: Two scientists have been award the 2024 Nobel Prize in Physiology or Medicine for their discovery of microRNA. Victor Ambros, professor of molecular medicine at the University of Massachusetts Chan Medical School, and Gary Ruvkun, professor of genetics at Harvard Medical School and an investigator at Massachusetts General Hospital, received the prize for revealing how microRNAs turn genes on and off. 
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twitter:title: Two Scientists Honored with Nobel Prize in Medicine For Their Discovery of MicroRNA
twitter:description: Two scientists have been award the 2024 Nobel Prize in Physiology or Medicine for their discovery of microRNA. Victor Ambros, professor of molecular medicine at the University of Massachusetts Chan Medical School, and Gary Ruvkun, professor of genetics at Harvard Medical School and an investigator at Massachusetts General Hospital, received the prize for revealing how microRNAs turn genes on and off. 
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* Science

# Two Scientists Honored with Nobel Prize in Medicine For Their Discovery of MicroRNA

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<!-- video src="https://cdn.jwplayer.com/manifests/k6g1mtvv.m3u8" -->
## Video: Two Scientists Honored with Nobel Prize in Medicine For Their Discovery of MicroRNA

[Watch (HLS stream): Two Scientists Honored with Nobel Prize in Medicine For Their Discovery of MicroRNA](https://cdn.jwplayer.com/manifests/k6g1mtvv.m3u8) (2:16)

![Two Scientists Honored with Nobel Prize in Medicine For Their Discovery of MicroRNA](https://cdn.jwplayer.com/v2/media/k6g1mtvv/poster.jpg?width=720)

_Published 2024-10-07. Two scientists have been award the 2024 Nobel Prize in Physiology or Medicine for their discovery of microRNA. Victor Ambros, professor of molecular medicine at the University of Massachusetts Chan Medical School, and Gary Ruvkun, professor of genetics at Harvard Medical School and an investigator at Massachusetts General Hospital, received the prize for revealing how microRNAs turn genes on and off._


---

Oct 7, 2024 8:20 PM UTC

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## Transcript

Nobel Assembly at Karlinsky Institute has today decided toward the 2024 Nobel Prize in Physiology or Medicine jointly to Victor Ambros and Gary Ravke for the discovery of Micro RNA and its role in post transcriptional gene regulation. I comment a Victor Ambrose 20. Gary and I knew we're studying interesting genes, probably that are components of some kind of developmental clock, right? And so we're just really curious about what kind of gene products would be mediating this kind of activity. The significance of this discovery of microRNAs is that it allowed us to be aware of a very complex and nuanced layer of regulation, whereby genes and our cells talk to each other and coordinate their activity.

Honestly, this was not something that I expected to be quite honest. And because in my opinion, the Nobel Prize to Mellow and Fire encompassed all these phenomena that we study. There are a lot of awards, but the Nobel is its own class in terms of how much attention it gets. So I don't know. I've probably gotten ten different awards over the last 20 years. There's never been a press conference like this or TV cameras or you know, nothing like this. So it's a completely different world. And the fact of the matter is, there's about 500,000 molecular biologists in the world now. And there's only 20,000 genes approximately, and that's spread out over every organism.

So the chances that somebody has worked on a gene you bump into is quite high, but they don't know that you're working on it, and you don't know they're working on it. And so there's plenty of chances for surprises. And the surprises are what keep you young in science. And so I am constantly surprised

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