--- title: FDA Approves Painkiller Designed To Deter Abuse | TIME description: The FDA approved a new drug that combines oxycodone with another drug that will make the pills useless if patients crush them, a sign the administration believes means users intend to inject or snort the drug to get high. canonical: https://time.com/video/Ymqv9uEa/ og:title: FDA Approves Painkiller Designed To Deter Abuse og:description: The FDA approved a new drug that combines oxycodone with another drug that will make the pills useless if patients crush them, a sign the administration believes means users intend to inject or snort the drug to get high. og:url: https://time.com/video/Ymqv9uEa/ og:image: https://cdn.jwplayer.com/v2/media/Ymqv9uEa/poster.jpg?width=720 og:type: video.other twitter:card: summary_large_image twitter:title: FDA Approves Painkiller Designed To Deter Abuse twitter:description: The FDA approved a new drug that combines oxycodone with another drug that will make the pills useless if patients crush them, a sign the administration believes means users intend to inject or snort the drug to get high. twitter:image: https://cdn.jwplayer.com/v2/media/Ymqv9uEa/poster.jpg?width=720 --- # FDA Approves Painkiller Designed To Deter Abuse > Sponsored content. 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They are at time.com/newsletters and are separate from a paid subscription. ## Video: FDA Approves Painkiller Designed To Deter Abuse [Watch (HLS stream): FDA Approves Painkiller Designed To Deter Abuse](https://cdn.jwplayer.com/manifests/Ymqv9uEa.m3u8) (2:09)  _Published 2014-07-24. The FDA approved a new drug that combines oxycodone with another drug that will make the pills useless if patients crush them, a sign the administration believes means users intend to inject or snort the drug to get high._ --- Jul 27, 2023 5:02 PM UTC --- ## More From This Series [All Videos](https://time.com/video/) [FDA Approves the First Non-Opioid Pain Medicine in 20 Years](/video/hiSBLkgk/) ### FDA Approves the First Non-Opioid Pain Medicine in 20 Years [The FDA Just Approved the First Drug for Postpartum Depression](/video/0zMw11Dm/) ### The FDA Just Approved the First Drug for Postpartum Depression [After 2 Rejections, FDA Approves Drug Dubbed 'Female Viagra'](/video/Zs5thHzC/) ### After 2 Rejections, FDA Approves Drug Dubbed 'Female Viagra' --- ## Transcript the fda just approved a new drug that combines a painkiller with something that blocks the pain killed why the drug called targinicer is a mix of painkiller oxy coninde and nyloxim. Naloxone blocks the euphoric effects of the pain killer, but it only activates if the pill gets physically crushed. So basically, if you do something the FDA believes is the first step towards snorting or injecting Oxycodone to get high. The Naloxone stops it. In a statement Wednesday, the FDA wrote, Encouraging the development of opioids with abuse- deterrent properties is just one component of a broader approach to reducing abuse and misuse. But treating drug addiction problems with more drugs is something that's going to bring out the skeptics. Keep in mind the maker of Targenic Purdue Pharma tried the same tactic with Oxycontin in 2010. By making a pill that had much less pay off for addicts if they crushed it. Only two years later the New England Journal of Medicine found people with opioid dependence that used Oxycontin as their drug of choice. Dropped from 36 % to 13. But it also found a problem, many of the addicts had simply switched to a more effective combination of other drugs including heroin. Researchers with the journal wrote, Thus, abuse- deterrent formulations may not be the magic bullets that many hoped they would be in solving the growing problem of opioid abuse. With Targinic the FDA even wrote, the drug shouldn't be for as needed pain relief, but for chronic pain patients who didn't respond well to other treatments. The Los Angeles Times take to multiple pain management experts who said, it's usually a better tactic for doctors to take more care in prescribing pain killers. Rather than switching to new drugs still one said the obvious alternative is not to have abuse- deterrent formulations, and I don't know anyone who would find that preferable. If taken orally and without crushing it, the FDA noted too much targiniq can still lead to over doses, just like oxycodone. 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