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---
description: Find out why Proprio Paradigm is on TIME&#x27;s list of 2025&#x27;s best inventions.
title: Proprio Paradigm: The Best Inventions of 2025
image: https://static.time.com/v3/assets/bltea6093859af6183b/blt1575c42c8c551096/6998ca611500fb68c7aa6a64/proprio-paradigm-TIME-best-inventions-2025.jpg?branch=production&amp;width=3840&amp;quality=75&amp;auto=webp&amp;crop=16:9
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Oct 09, 2025

# Proprio Paradigm

Making real-time maps for surgeons

by 

[Matt Fuchs](/author/matt-fuchs/)


## Matt Fuchs


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Matt Fuchs writes about science, health, aging, and well-being. His Substack is Prime Factors and he is a 2026-2027 Knight-Wallace Fellow. 

![](https://static.time.com/v3/assets/bltea6093859af6183b/blt1575c42c8c551096/6998ca611500fb68c7aa6a64/proprio-paradigm-TIME-best-inventions-2025.jpg?branch=production&width=3840&quality=75&auto=webp&crop=3:2)

Courtesy Proprio

Over [1 million](https://www.jointcommission.org/en-us/certification/orthopedic "undefined") spine surgeries are performed annually in the U.S., but [success rates are low](https://pmc.ncbi.nlm.nih.gov/articles/PMC5913031/ "undefined"), leading to repeat operations. Proprio’s Paradigm is an [FDA-cleared](https://www.americanhhm.com/technotrends/fda-approved-proprios-first-of-its-kind-ai-surgical-guidance-technology "undefined"), real-time 3D surgical guidance system to improve outcomes. It uses arrays of sensors and cameras to build a live digital twin of the patient’s body that acts as a map—and also requires fewer traditional scans, thus reducing radiation exposure. The platform has already been used in over 100 procedures with revision-surgery risk dropping from about 50% to less than 10%, the company says. After its [first clearance](https://www.propriovision.com/news/first-light-field-enabled-spine-surgery-navigation-platform-proprio-paradigm-tm-receives-fda-clearance "undefined") in 2023, Paradigm has rolled out to [top medical centers](https://www.propriovision.com/news/proprio-receives-fda-clearance-for-the-worlds-first-ai-surgical-guidance-platform "undefined") such as Duke Health.

These are independent reviews of the products mentioned, but TIME receives a commission when purchases are made through affiliate links at no additional cost to the purchaser.


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