--- description: Find out why AngioDynamics NanoKnife is on TIME's list of 2025's best inventions. title: AngioDynamics NanoKnife: The Best Inventions of 2025 image: https://static.time.com/v3/assets/bltea6093859af6183b/bltf6648685694cea2c/6998ca66f1b08283c66f1c1c/AngioDynamics-TIME-best-inventions-2025.png?branch=production&width=3840&quality=75&auto=webp&crop=16:9 --- Oct 09, 2025 # AngioDynamics NanoKnife A minimally invasive prostate cancer treatment by [Allana Akhtar](/author/allana-akhtar/) ## Allana Akhtar Update your preferences in [Account Settings](/account/preferences/) Close  Courtesy AngioDynamics NanoKnife delivers a localized electrical pulse that can treat prostate cancer. Developed by medical device firm AngioDynamics and cleared by the Food and Drug Administration in December 2024, it offers men with intermediate-risk cases of prostate cancer a minimally invasive option before doctors turn to radiation or other traditional cancer treatments that can damage nearby nerves. “It's not therapy that is appropriate for all men,” says David Golombos, a urologic oncologist at Robert Wood Johnson University Hospital in N.J., “but this serves as a great option to treat localized prostate cancer, minimizing quality of life side effects” like erectile dysfunction. These are independent reviews of the products mentioned, but TIME receives a commission when purchases are made through affiliate links at no additional cost to the purchaser. ```json [{"@context":"https://schema.org","@type":"Article","@id":"https://time.com/collections/best-inventions-2025/7318433/angiodynamics-nanoknife/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/collections/best-inventions-2025/7318433/angiodynamics-nanoknife/"},"headline":"AngioDynamics NanoKnife","datePublished":"2025-10-09T11:00:17.000Z","dateModified":"2026-04-13T11:54:54.152Z","description":"","url":"https://time.com/collections/best-inventions-2025/7318433/angiodynamics-nanoknife/","keywords":["Tech","E-Commerce","list","franchise","Magazine","best inventions","Special Project","sponsorshipblock","Accolades","Best Inventions 2025"],"thumbnailUrl":"https://static.time.com/v3/assets/bltea6093859af6183b/bltf6648685694cea2c/6998ca66f1b08283c66f1c1c/AngioDynamics-TIME-best-inventions-2025.png?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","author":[{"@type":"Person","name":"Allana Akhtar","jobTitle":null,"url":"https://time.com/author/allana-akhtar/"}],"creator":"Allana Akhtar","articleSection":"Business","image":[{"@type":"ImageObject","url":"https://static.time.com/v3/assets/bltea6093859af6183b/bltf6648685694cea2c/6998ca66f1b08283c66f1c1c/AngioDynamics-TIME-best-inventions-2025.png?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","width":1200,"height":675}],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/business/","name":"Business"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/time-section-tech/","name":"Tech"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/collections/best-inventions-2025/7318433/angiodynamics-nanoknife/","name":"AngioDynamics NanoKnife"}}]}] ```