--- description: Find out why Pelage Pharmaceuticals PP405 is on TIME's list of 2025's best inventions. title: Pelage Pharmaceuticals PP405: The Best Inventions of 2025 image: https://static.time.com/v3/assets/bltea6093859af6183b/blt9ff3d9196b56a5a3/6998ca32a97fc0ca49a74b6a/pelage-pharmaceuticals-PP405-TIME-best-inventions-2025.jpg?branch=production&width=3840&quality=75&auto=webp&crop=16:9 --- Oct 09, 2025 # Pelage Pharmaceuticals PP405 A therapy to reverse balding by [Allana Akhtar](/author/allana-akhtar/) ## Allana Akhtar Update your preferences in [Account Settings](/account/preferences/) Close  Courtesy Pelage Pharmaceuticals PP405 is a topical, non-hormonal treatment that activates dormant stem cells in hair follicles to regrow hair back to fullness. Clinical trials have shown success, though the drug may not work in the end stages of balding if the follicle is scarred. Pelage Pharmaceuticals is still awaiting further trial results before it can receive FDA approval, but the drug’s success could open doors for future therapies. “It’s not covering up the symptoms, it’s targeting the underlying biology,” says Pelage Pharmaceuticals chief medical officer Christina Weng. **Correction, Oct. 9** _The original version of this story misstated the limited of the drug's efficacy. It may not work in the end stages of balding if the follicle is scarred, but it doesn't only work in the early stages of balding._ These are independent reviews of the products mentioned, but TIME receives a commission when purchases are made through affiliate links at no additional cost to the purchaser. ```json [{"@context":"https://schema.org","@type":"Article","@id":"https://time.com/collections/best-inventions-2025/7318256/pelage-pharmaceuticals-pp405/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/collections/best-inventions-2025/7318256/pelage-pharmaceuticals-pp405/"},"headline":"Pelage Pharmaceuticals PP405","datePublished":"2025-10-09T11:00:16.000Z","dateModified":"2026-04-13T11:54:46.868Z","description":"","url":"https://time.com/collections/best-inventions-2025/7318256/pelage-pharmaceuticals-pp405/","keywords":["Tech","E-Commerce","list","franchise","Magazine","best inventions","Special Project","sponsorshipblock","Accolades","Best Inventions 2025"],"thumbnailUrl":"https://static.time.com/v3/assets/bltea6093859af6183b/blt9ff3d9196b56a5a3/6998ca32a97fc0ca49a74b6a/pelage-pharmaceuticals-PP405-TIME-best-inventions-2025.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","author":[{"@type":"Person","name":"Allana Akhtar","jobTitle":null,"url":"https://time.com/author/allana-akhtar/"}],"creator":"Allana Akhtar","articleSection":"Business","image":[{"@type":"ImageObject","url":"https://static.time.com/v3/assets/bltea6093859af6183b/blt9ff3d9196b56a5a3/6998ca32a97fc0ca49a74b6a/pelage-pharmaceuticals-PP405-TIME-best-inventions-2025.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","width":1200,"height":675}],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/business/","name":"Business"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/time-section-tech/","name":"Tech"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/collections/best-inventions-2025/7318256/pelage-pharmaceuticals-pp405/","name":"Pelage Pharmaceuticals PP405"}}]}] ```