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Droplette co-founders Madhavi Gavini and Rathi Srinivas knew that most of the topical serums people use on their face simply evaporate, and they set out to create a painless way to get more product under the skin. Their patented technology transforms water-based serums, such as collagen, glycolic acid, and retinol, into aerosols and then into tiny micro-droplets that their research shows penetrate the skin’s barrier 20 times as deep as topical creams. Gavini and Srinivas are now pursuing FDA approval to use the device to administer topical drugs for medical conditions like epidermolysis bullosa, a rare disease that causes blistering skin.

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