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# How Pfizer Is Rethinking What’s Possible in Cancer Care

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<!-- video src="https://cdn.jwplayer.com/manifests/ybjX4AlJ.m3u8" -->
## Video: Pfizer x TIME Studios

[Watch (HLS stream): Pfizer x TIME Studios](https://cdn.jwplayer.com/manifests/ybjX4AlJ.m3u8) (4:04)

![Pfizer x TIME Studios](https://cdn.jwplayer.com/v2/media/ybjX4AlJ/poster.jpg?width=720)

_Published 2026-10-21. Pfizer x TIME Studios_

#### _Jeff Legos, Pfizer’s Chief Oncology Officer, on the science, technology and stories behind the next generation of breakthroughs._

Fifteen years ago, Jeff Legos met a patient who had just been told his cancer had returned and it was likely untreatable. Years later, Jeff learned that the patient was able to join a new clinical trial, which he credited with saving his life. The experience brought into sharp focus what is ultimately at stake in cancer research: time. 

“Every moment matters,” says Legos, Pfizer’s Chief Oncology Officer. For him, the fight against cancer is deeply personal, firmly grounded in science and urgently needed. “I am incredibly inspired by patients, I am driven by science, and I strive for a world without cancer,” he says.

That sense of urgency continues to shape his work today. At Pfizer, the ambition is to deliver eight cancer breakthroughs by 2030, helping create more meaningful moments for people living with cancer and their families.

Legos points to the company’s work across cancer research, from understanding the underlying biology to creating targeted medicines that carry treatments directly to cancer cells. Increasingly, he says, the goal is to combine multiple treatment approaches guided by the biology of each patient’s cancer. 

Artificial intelligence is further accelerating that work. By drawing on years of clinical data and scientific expertise, Pfizer is using AI to help researchers identify promising molecules and targets, while conducting simulations to help determine which clinical trial approaches have the highest probability of success. Pfizer is already embedding AI into clinical trial design and execution, with some processes that once took years happening roughly 50% faster.

For Legos, however, speed only matters if it translates into progress for patients. 

“Patients are waiting and families are counting on us,” he says. Their courage, he adds, reinforces the responsibility to keep learning and “never resting on yesterday’s progress.”

Because better cancer care is not measured by scientific progress alone, but by the moments that progress makes possible.

[![](https://static.time.com/v3/assets/bltea6093859af6183b/bltbabbc847338b4c7c/69fdfc0c9029926786e8af34/pfizer-logo-white.png?branch=production&width=256&quality=75&auto=webp)](https://www.pfizer.com/science/focus-areas/oncology)

[Learn More](https://www.pfizer.com/science/focus-areas/oncology)

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