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title: Do I Know You?
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* [Health](/section/health/)

# Do I Know You?

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## TIME Health Matters: Reference Facts and FAQ

### Definition

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#### What is TIME's health newsletter?

Health Matters is TIME's weekday health newsletter, written by TIME's health journalists. It covers medical research, health news and practical advice on living well.

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### Sources

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by 

[Sora Song](https://time.com/author/sora-song/)

Jul 17, 2006 4:00 AM UTC

by 

[Sora Song](https://time.com/author/sora-song/)

Jul 17, 2006 4:00 AM UTC

Cecilia Burman has always had a problem with faces. As a child, she struggled to pick out her own face in school photos, and she is hard-pressed today to describe her mother’s features. Over the years she has offended countless friends, passing them on neighborhood streets or in office hallways like strangers. “People think I’m just snobby,” says Burman, 38, a computer consultant in Stockholm. “It makes me really, really sad to lose new friends because they think I couldn’t bother to say hello.”

There’s a name for Burman’s condition: prosopagnosia or, more informally, face blindness. The disorder was thought to be exceedingly rare and mainly a result of brain injury. Until a few years ago, there were perhaps 100 documented cases, says Ken Nakayama, a professor of psychology at Harvard. But last month a team of German researchers took the first stab at charting its prevalence, and the results, published in the American Journal of Medical Genetics, were remarkable. The new study showed that prosopagnosia (from the Greek prosopon for face and agnosia for ignorance) is highly heritable and surprisingly common, afflicting, in some form, about 1 in 50 people–more than 5 million in the U.S. alone. “That’s huge,” says Dr. Thomas GrÃ¼ter of the Institute of Human Genetics in MÃ¼nster, an author of the paper and himself a prosopagnosic. “It was a real surprise.” 

[(See ways you can live for 100 years.)](http://www.time.com/time/specials/packages/0,28757,1963392,00.html) 

Within that group of sufferers, however, the condition varies widely. For the vast majority, the problem is not so much about detecting a face–prosopagnosics can see eyes, noses and mouths as clearly as anyone else–as it is about recognizing the same set of features when seeing them again. It’s a disability that complicates everything from following a movie plot to picking a perp out of a lineup. While mild prosopagnosics can train themselves to memorize a limited number of faces (it’s said to be like learning to distinguish one stone from another), others grapple with identifying family members and, in extreme cases, their own face. Gaylen Howard, 40, a homemaker in Boulder, Colo., says that when she’s standing in front of a mirror in a crowded restroom, she makes a funny face so that, as she puts it, “I can tell which one is me.”

Most prosopagnosics learn to cope early on. They distinguish people based on cues like hairstyle, voice, gait or body shape. They avoid places where they could unexpectedly run into someone they know. They pretend to be lost in thought while walking down the street. They act friendly to everyone–or to no one. In short, they become expert at masking their dysfunction. “This is probably why \[the disorder\] went unnoticed for so long,” says GrÃ¼ter.

In the new study, GrÃ¼ter and his colleagues surveyed 689 local high school and medical students and diagnosed the disorder in 17\. Further interviews with the families of 14 of these subjects revealed that each had at least one close relative with the same problem. Judging from the patterns of inheritance, GrÃ¼ter speculates that prosopagnosia may be caused by a defect in a single, dominant gene, so that if one parent has it, each child has a 50% chance of inheriting it.

Howard is one of those children. Last year she learned the term prosopagnosia from a news article and thought, I have that. She contacted Bradley Duchaine of University College London, who jointly runs the Prosopagnosia Research Centers with Harvard’s Nakayama. Last April, Duchaine gave Howard, her parents and six of her seven siblings a battery of recognition tests, including one that required identifying celebrity faces. Every member of the Howard family scored below average. “I showed one of them Elvis Presley,” Duchaine says, “and she thought it was Brooke Shields.”

Neuroscientists aren’t sure exactly how the brain perceives faces but know that some ability to do so is present from birth and involves large and broadly distributed parts of the brain– presumably reflecting the importance of face perception to survival. Babies prefer looking at their mother’s visage over a stranger’s and quickly learn to distinguish between male and female faces. Some part of that circuitry seems to be broken in prosopagnosics. Brain scans suggest impairment in the temporal or occipital lobes, both of which are heavily involved in face recognition.

For now, it’s enough for face-blind people like Burman, who has spent a lifetime being misjudged as lazy and uncaring, to know that there are many others out there like her. Burman made her first contact with fellow prosopagnosics on an Internet mailing list in 2000\. “It was only then that I really recognized my own situation in theirs,” she says. “It was such a relief. I cried for days.”

[See TIME’s Pictures of the Week.](http://www.time.com/time/picturesoftheweek) 

[See the Cartoons of the Week.](http://www.time.com/time/cartoonsoftheweek)

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