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title: University of Oxford and the Serum Institute of India R21/Matrix-M: the 200 Best Inventions of 2024
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og:description: Find out why University of Oxford and the Serum Institute of India R21/Matrix-M made this year's list
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Oct 30, 2024

# A Game-Changing Vaccine

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by 

[Alice Park](https://time.com/author/alice-park/)


## Alice Park


Senior Correspondent

![Malaria vaccines](https://static.time.com/v3/assets/bltea6093859af6183b/bltb9d45c8e91aefdfb/698a8a1e09208fd958422493/Malaria-Vaccine-best-inventions.jpeg?branch=production&width=1200&quality=75&auto=webp&crop=3:2)

In this photograph taken on February 27, 2024, a staff inspects vials of the R21 Malaria Vaccine at the Serum Institute of India (SII) headquarters in Hadapsar, Pune.

In this photograph taken on February 27, 2024, a staff inspects vials of the R21 Malaria Vaccine at the Serum Institute of India (SII) headquarters in Hadapsar, Pune. Indranil Mukherjee—AFP/Getty Images

After decades of slow development, the World Health Organization recently recommended two vaccines to combat malaria, which [infects](https://www.cdc.gov/malaria/php/impact/index.html) hundreds of millions and kills 600,000 people each year. Researchers at Oxford University and the Serum Institute of India developed the latest shot, R21/Matrix-M, and released it in 2023\. The vaccine targets the malaria antigen R21, and includes an adjuvant from Novavax, which helps to amplify the immune response generated by the shot. Serum began shipping the first doses, which cost under $4 per shot, in [May](https://www.seruminstitute.com/press%5Frelease%5Fsii%5F200524.php) 2024, and CEO Adar Poonawalla anticipates continuing to provide 50 to 60 million doses annually to Africa, where malaria remains endemic, over the next three years. “We have the capacity, the demand, and the will of the people to want this vaccine,” he says.

These are independent reviews of the products mentioned, but TIME receives a commission when purchases are made through affiliate links at no additional cost to the purchaser.


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