--- description: Find out why Rion Aesthetics Plated Intense Serum is one of the best inventions of 2024 title: Rion Aesthetics Plated Intense Serum: the 200 Best Inventions of 2024 image: https://static.time.com/v3/assets/bltea6093859af6183b/blt0d9dde8635a56701/698a8a00186892744e6cd330/Plated-INTENSE-Serum-best-inventions-2024.jpeg?branch=production&width=3840&quality=75&auto=webp&crop=16:9 --- Oct 30, 2024 # Medically-Backed Anti-Aging Serum by [Jessica Klein](/author/jessica-klein/) ## Jessica Klein Update your preferences in [Account Settings](/account/preferences/) Close  “If you cut yourself, what's the first responder?” says Rion Aesthetics CEO Alisa Lask. “Platelets—your blood.” Going off that premise, [creators](https://www.rionaesthetics.com/our-products "undefined") of Rion’s Plated Intense Serum purchase platelets from a blood bank to harness the type of exosome—an inter-cellular messenger—responsible for signaling cell renewal. With billions of exosomes per two-pump dose, Plated uses its Renewosome technology to decrease facial redness and maintain shelf stability of the serum—a challenge for stem cell-containing products. The company has the medical credentials: Rion was founded by Mayo Clinic physicians at the Van Cleve Cardiac Regenerative Medicine Program, where they discovered that exosomes play a key role in healing. The company now produces platelet-derived exosome products currently in clinical trials for wound healing, cardiology, and orthopedics, while Lask’s spinoff focuses on aesthetic applications. A 2023 clinical[ study](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617900/ "undefined") found that “all patients experienced improvement in redness, skin irritation, skin tone, texture, and smoothness” with nine weeks of Plated use. **Buy Now:** INTENSE Serum on [Plated SkinScience](https://fave.co/3YpXwym "undefined") These are independent reviews of the products mentioned, but TIME receives a commission when purchases are made through affiliate links at no additional cost to the purchaser. Rion Aesthetics Plated Intense Serum: the 200 Best Inventions of 2024 ```json [{"@context":"https://schema.org","@type":"Article","@id":"https://time.com/collections/best-inventions-2024/7094564/rion-aesthetics-plated-intense-serum/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/collections/best-inventions-2024/7094564/rion-aesthetics-plated-intense-serum/"},"headline":"Rion Aesthetics Plated Intense Serum: the 200 Best Inventions of 2024","datePublished":"2024-10-30T12:01:04.000Z","dateModified":"2026-04-13T11:54:26.096Z","description":"Find out why Rion Aesthetics Plated Intense Serum is one of the best inventions of 2024","url":"https://time.com/collections/best-inventions-2024/7094564/rion-aesthetics-plated-intense-serum/","keywords":["Tech","E-Commerce","list","franchise","Magazine","best inventions"],"thumbnailUrl":"https://static.time.com/v3/assets/bltea6093859af6183b/blt0d9dde8635a56701/698a8a00186892744e6cd330/Plated-INTENSE-Serum-best-inventions-2024.jpeg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","author":[{"@type":"Person","name":"Jessica Klein","jobTitle":null,"url":"https://time.com/author/jessica-klein/"}],"creator":"Jessica Klein","articleSection":"Business","image":[{"@type":"ImageObject","url":"https://static.time.com/v3/assets/bltea6093859af6183b/blt0d9dde8635a56701/698a8a00186892744e6cd330/Plated-INTENSE-Serum-best-inventions-2024.jpeg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","width":1200,"height":675}],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/business/","name":"Business"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/time-section-tech/","name":"Tech"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/collections/best-inventions-2024/7094564/rion-aesthetics-plated-intense-serum/","name":"Rion Aesthetics Plated Intense Serum: the 200 Best Inventions of 2024"}}]}] ```