For David Sinclair, the pursuit of youth had a humble start — in yeast. A professor of genetics at Harvard Medical School, he identified genes that allow yeast to get by on fewer calories and extend their life span by about 30%. Nice for yeast — not for hungry humans.
Last year, Sinclair upped his game and pinned down a chemical known as NAD that actually reverses the aging process in cells. NAD levels tend to drop by as much as 50% as we get older; if we could restore what’s lost, aging cells might behave as if they were younger. Immortality is out of reach, but living more years with a body that’s robust enough to make the most of them is a real possibility.
Agus is a professor of medicine and the author of A Short Guide to a Long Life
- How to Help Victims of the Texas School Shooting
- TIME's 100 Most Influential People of 2022
- What the Buffalo Tragedy Has to Do With the Effort to Overturn Roe
- Column: The U.S. Failed Miserably on COVID-19. Canada Shows It Didn't Have to Be That Way
- N.Y. Will Soon Require Businesses to Post Salaries in Job Listings. Here's What Happened When Colorado Did It
- The 46 Most Anticipated Movies of Summer 2022
- ‘We Are in a Moment of Reckoning.’ Amanda Nguyen on Taking the Fight for Sexual Violence Survivors to the U.N.