--- title: Moderna Says Its RSV Vaccine Works Based on New Data description: Newly reported results from a late-stage human trial suggest Moderna's mRNA vaccine platform will work against another viral infection. canonical: https://time.com/6247812/moderna-rsv-vaccine-data/ author: Alice Park article:opinion: false article:content_tier: free article:published_time: 2023-01-18T16:10:16.000Z article:modified_time: 2026-02-24T15:17:39.487Z article:section: Health og:title: Moderna Says Its RSV Vaccine Works og:description: New results from a late-stage human trial suggest Moderna's mRNA vaccine platform will work for a range of viruses. og:url: https://time.com/6247812/moderna-rsv-vaccine-data/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt141b913721587aaf/698a39810116822152982a9d/GettyImages-1294264403.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9 og:image:width: 2202 og:image:height: 1239 og:image:alt: Close up of older woman getting injected with a vaccine in upper arm. og:type: article twitter:card: summary_large_image twitter:title: Moderna Says Its RSV Vaccine Works twitter:description: New results from a late-stage human trial suggest Moderna's mRNA vaccine platform will work for a range of viruses. twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/blt141b913721587aaf/698a39810116822152982a9d/GettyImages-1294264403.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9 ---  # Moderna's mRNA-Based RSV Vaccine Just Passed a Major Test > Sponsored content. 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Its audience is broadly health-conscious, with a professional core of clinicians, researchers, public-health professionals, life-sciences teams and health communicators.  by [Alice Park](https://time.com/author/alice-park/)  ## Alice Park Senior Correspondent Jan 18, 2023 4:10 PM UTC  Getty Images/Cavan Images RF  by [Alice Park](https://time.com/author/alice-park/)  ## Alice Park Senior Correspondent Jan 18, 2023 4:10 PM UTC Moderna has become a well-known name thanks to its highly effective COVID-19 vaccine, based on mRNA technology. But even before the pandemic hit, the company was developing an mRNA-based vaccine against another scourge, respiratory syncytial virus (RSV), which primarily affects infants and the elderly. In a release issued on Jan. 17, the Massachusetts-based company said an early look at data from the late-stage trial of its RSV vaccine shows that the shot is effective. Among 37,000 people over age 60 in 22 countries, the vaccine was 83.7% effective in reducing moderate RSV illness, defined as two or more symptoms of the disease, and 82.4% effective in reducing more severe illness encompassing three or more symptoms compared to those receiving placebo. As RSV progresses, people move from cold-like symptoms to more severe respiratory distress and damage, including wheezing, difficulty breathing, and inflammation of the lungs. The trial is ongoing, but based on the positive results, Moderna plans to file a request for approval of the vaccine from the Food and Drug Administration (FDA) this year. In doing so, Moderna would join Pfizer, which [submitted a request](https://www.pfizer.com/news/press-release/press-release-detail/us-fda-accepts-priority-review-biologics-license-0) for expedited review of its RSV vaccine for older adults last December. The company reported results similar to Moderna’s—it was 86% effective in reducing severe respiratory illness. Pfizer is also developing a [RSV vaccine for pregnant women](https://time.com/6226678/rsv-virus-kids-babies-symptoms/), who would be immunized to [protect their newborns](https://www.pfizer.com/news/press-release/press-release-detail/pfizer-announces-positive-top-line-data-phase-3-global) after delivery. Dr. Paul Burton, chief medical officer at Moderna, says that the company’s experience in developing the COVID-19 mRNA vaccine played a “huge” role in the development of the RSV shot. “MRNA as a platform is predictable, synthesizeable, and has high fidelity,” he says. “The pandemic did a couple of things: It helped us to understand the importance of respiratory viruses and how we can protect against them, and provided a platform that has been tried and tested in an unprecedented number of people, which gives us extraordinary confidence \[in the safety and effectiveness of the vaccine\].” Each year, 58,000 to 80,000 children under age five are [hospitalized](https://www.cdc.gov/rsv/research/index.html) for RSV in the U.S., including many premature infants, who are at highest risk for the respiratory illness. Some 100 to 300 children die from the infection. Among [adults over age 65](https://www.cdc.gov/rsv/research/index.html), there are 60,000 to 120,000 hospitalizations each year, and 6,000 to 10,000 deaths. During the 2022-2023 winter season, rates of RSV, along with the seasonal flu, began climbing early in the fall, as children shielded from infections during the COVID-19 pandemic by lockdowns and remote learning returned to school and were exposed to RSV for the first time. By late December, monthly RSV cases in the U.S. [peaked](https://www.cdc.gov/surveillance/nrevss/rsv/natl-trend.html) at about 19,500 cases. Burton says the company has five additional trials ongoing involving the RSV vaccine, including in young children and pregnant women. They are also testing the RSV shot in combination with other vaccines, such as influenza and COVID-19\. “Our ambition is to bring two to three vaccines together into a single shot to provide broad protection against all sorts of different respiratory viruses,” he says. “The advantage in compliance and adherence would be extremely powerful.” ```json [{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/6247812/moderna-rsv-vaccine-data/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/6247812/moderna-rsv-vaccine-data/"},"headline":"Moderna's mRNA-Based RSV Vaccine Just Passed a Major Test","datePublished":"2023-01-18T16:10:16.000Z","dateModified":"2026-02-24T15:17:39.487Z","description":"Newly reported results from a late-stage human trial suggest Moderna's mRNA vaccine platform will work against another viral infection.","url":"https://time.com/6247812/moderna-rsv-vaccine-data/","keywords":["Technology","COVID-19","healthscienceclimate"],"thumbnailUrl":"https://static.time.com/v3/assets/bltea6093859af6183b/blt141b913721587aaf/698a39810116822152982a9d/GettyImages-1294264403.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","author":[{"@type":"Person","name":"Alice Park","jobTitle":"Senior Correspondent","url":"https://time.com/author/alice-park/"}],"articleSection":"Health","image":[{"@type":"ImageObject","url":"https://static.time.com/v3/assets/bltea6093859af6183b/blt141b913721587aaf/698a39810116822152982a9d/GettyImages-1294264403.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","width":1200,"height":675,"headline":"Close up of older woman getting injected with a vaccine in upper arm.","caption":"Close up of older woman getting injected with a vaccine in upper arm.","creditText":"Getty Images/Cavan Images RF","representativeOfPage":true}],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/health/","name":"Health"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/technology/","name":"Technology"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/6247812/moderna-rsv-vaccine-data/","name":"Moderna's mRNA-Based RSV Vaccine Just Passed a Major Test"}}]}] ```