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Alexandra Sifferlin’s Jan. 16 cover story about the many medicinal uses of Botox spurred readers to share a variety of personal experiences. On Facebook, some wrote that they have used the drug–which is most famous for smoothing wrinkles–to treat everything from migraines and excessive sweating to extreme morning sickness and poststroke conditions. But Warren I. Schaeffer, a former professor of microbiology in Edison, N.J., said that he wished the story had included more discussion of reports that “the effectiveness of the treatment does diminish with repeated use over time,” as that could “put a financial strain on the patient as effectiveness diminishes but cost per dose remains.”


Susanna Schrobsdorff struck a chord with readers in her Jan. 16 column about how the passage of time can change family dynamics and her reflection on the deaths of celebrity mother-daughter pair Debbie Reynolds and Carrie Fisher. Roland Jolsvay of Minnetonka, Minn.–who said he is “well north of 60” but still feels 24 inside–said the column “put into words” the feelings he has had “for a couple of years now as I watch my children and grandchildren progress on their own paths” and made him proud to have cultivated “a family dynamic that puts a premium on taking care of each other.”


TIME’s video-game critic Matt Peckham has selected the 50 games he’s most excited to play in 2017, from Agents of Mayhem to The Legend of Zelda: Breath of the Wild. See all his picks at time.com/2017games


TIME asked 12 White House photographers to share images of cherished moments with U.S. Presidents. Pete Souza, who worked for Barack Obama and Ronald Reagan, chose this 1988 photo of Reagan in the Oval Office. See more at time.com/prez-photos


TIME Labs crunched 2015 data from the OECD to compare the average workweek in the world’s most productive countries. As the top five show, longer hours aren’t always the best. See the full list at time.com/worker-productivity

[This article contains a table. Please see hardcopy of magazine or PDF.]

RANK COUNTRY GDP PER HOUR WORKED AVERAGE WORKWEEK (IN HOURS) 1 Luxembourg $93.40 29 2 Ireland $87.30 33.5 3 Norway $81.30 27.3 4 Belgium $69.70 29.8 5 U.S. $68.30 33.6

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