July 7, 2016 9:57 AM EDT

It looks like Jon Jones, the interim UFC light heavyweight champion, won’t be fighting in the main event of the UFC 200.

The fighter was pulled from the event Wednesday night after the U.S. Anti-Doping Agency told Jones about a potential doping violation, ESPN reported. UFC president Dana White announced the change in a press conference just three days before Jones was set to face off against Daniel Cormier on Saturday.

“He’s got the chance to prove himself innocent before being called guilty,” White said, according to The Guardian. “But if it’s true, obviously super disappointing.”

Jones tested positive for a banned substance in an out-of-competition sample taken June 16 by USADA. This is not the first time Jones has failed drug tests around big fights. He had problems with drug testing around two of his last three fights, and while White did not know what substance was found in Jones’ test, this violation could land the fighter with a multiyear suspension.

Brock Lesnar’s heavyweight fight against Mark Hunt will be the new UFC 200 main event on Saturday in Las Vegas.

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Write to Abigail Abrams at abigail.abrams@time.com.

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