Over 30 years ago, Dr. Howard W. Jones Jr. paved the way for the creation of families in the U.S. once thought to be impossible.
Jones, who died July 31 at 104, advanced in vitro fertilization (IVF) and, in collaboration with his late wife Dr. Georgeanna Seegar Jones, was responsible for the birth of the first test-tube baby in the U.S., in 1981. A trailblazer for reproductive medicine, he also performed some of the first sex-change operations.
Despite being over 100, Jones worked regularly until he was hospitalized in July. He died of respiratory failure. “If I have a legacy,” he once said, “it’s of someone who … did not have any qualms about proceeding with the unknown because it was fun to do.”
More Must-Reads from TIME
- Inside Elon Musk’s War on Washington
- Why Do More Young Adults Have Cancer?
- Colman Domingo Leads With Radical Love
- 11 New Books to Read in February
- How to Get Better at Doing Things Alone
- Cecily Strong on Goober the Clown
- Column: The Rise of America’s Broligarchy
- Introducing the 2025 Closers
Contact us at letters@time.com