November 12, 2014 6:43 AM EST

The actress best known for her role as the voice of a lead character’s mother on the hit comedy “The Big Bang Theory” died Tuesday after a brief battle with cancer, her representatives said. Carol Ann Susi played the voice of Mrs. Wolowitz, Howard Wolowitz’s mom, on the program.

“The Big Bang Theory family has lost a beloved member today with the passing of Carol Ann Susi, who hilariously and memorably voiced the role of Mrs. Wolowitz,” Warner Bros. Television, CBS and the show’s producers said in a statement.

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