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1 of 11Nerds of the world take heart: This is how the future "Sexiest Man Alive" looked in middle school.Chris Bott—Splash News/Corbis -
2 of 11Clooney played George Burnett on "The Facts of Life" from 1985-1987.Ron Tom—NBC/Getty Images -
3 of 11Clooney married Talia Balsam in 1989. They divorced three years later.Ron Galella—WireImage -
4 of 11Clooney premiered in his breakout role as Dr. Doug Ross on ER in 1994.Sven Arnstein—NBC/Getty Images -
5 of 11In 1996 Clooney appeared in From Dusk Till Dawn, his first successful movie. -
6 of 11Clooney was voted People's Sexiest Man Alive for the first time in 1997 (he would win again in 2006).Sunset/Warner Bros. -
7 of 11Clooney tore his dura mater while filming Syriana in 2005, causing spinal fluid to leak out of his nose. He had to undergo two surgeries to repair it.Warner Brothers -
8 of 11In 2006 Clooney was the first person in Oscars history to be nominated for best director (Good Night and Good Luck) and best actor (Syriana) in different movies in the same year.Reed Saxon—AP -
9 of 11Clooney was on the cover of TIME Magazine in 2008.TIME -
10 of 11Clooney won the Bob Hope Humanitarian Emmy in 2010 for his work for the victims of the Haitian earthquake.Kevin Winter—Getty Images -
11 of 11In 2014 Clooney proposed to girlfriend Amal Alamuddin, despite claims that he would never marry again.Andres Solaro—AFP/Getty Images
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