Researchers say childhood adversity and psychiatric disorders may be linked to cellular changes that cause aging
Childhood trauma and psychiatric conditions may cause individuals to experience accelerated aging, according to research published last week.
In a study featured in Biological Psychiatry, scientists say they may have found evidence to suggest there is a link between aging at the cellular level and trauma or stress disorders.
To complete the study, researchers recruited 299 adults and separated them into different groups based on their experiences with childhood adversity, depression, anxiety or substance abuse.
The participants then had their DNA analyzed to study the lengths of their telomeres and any alterations to mitochondrial DNA (mtDNA). Telomere shortening and higher mtDNA content can serve as a yardstick to measure cellular aging.
“Results of the study show childhood adversity and lifetime psychopathology were each associated with shorter telomeres and higher mtDNA content,” read the report.
These effects were seen particularly in adults who had battled with major depression and anxiety disorders, along with parental loss or childhood maltreatment.
“Identifying the changes that occur at a cellular level due to these psychosocial factors allows us to understand the causes of these poor health conditions and possibly the overall aging process,” said Audrey Tyrka, associate professor of psychiatry and human behavior at Brown University.