Updated 4:08pm ET
Multiple tornados and severe thunderstorms are forecast this weekend from Nebraska to Texas, in what could be the worst severe weather event of the season so far.
The storms are expected to begin late Saturday and could last into the night before spreading to other areas, according to AccuWeather.com.
Multiple tornados had already touched down in eastern North Carolina by Saturday afternoon, sending 16 people to the emergency room so far and destroying or damaging 200 homes, CBS News reports.
"South-central Kansas to west-central Oklahoma would be in an elevated risk area for severe weather Saturday evening," meteorologist Scott Breit said. The storms could then move in the direction of Omaha, Neb., Wichita, Kan., Oklahoma City, and Dallas later at night.
Sunday could see more tornados and strong hail lasting into the evening as well, according to National Weather Service's Storm Prediction Center. It warned that Saturday's storms would be severe, but "isolated and scattered."
The relatively tame severe weather season so far makes the upcoming inclement weather a particular source of worry. "A reason for extra concern this weekend is that tornadoes have been nearly non-existent so far and people tend to forget what they have learned from year to year," said Accuweather senior vice president Mike Smith.