--- title: Tamiflu Not as Effective as We Think description: The antiviral drug isn’t any better than other treatments for the flu, leading experts to question why countries stockpile the medication canonical: https://time.com/57480/tamiflu-study-relenza/ author: Alice Park article:opinion: false article:content_tier: free article:published_time: 2014-04-10T15:22:08.000Z article:modified_time: 2026-02-21T07:14:38.654Z article:section: Health og:title: Next time you get the flu, you might skip antiviral drugs like tamiflu og:description: The antiviral drug isn’t any better than other treatments for the flu, leading experts to question why countries stockpile the medication og:url: https://time.com/57480/tamiflu-study-relenza/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production og:image:width: 1200 og:image:height: 675 og:image:alt: TIME og:type: article twitter:card: summary_large_image twitter:title: Next time you get the flu, you might skip antiviral drugs like tamiflu twitter:description: The antiviral drug isn’t any better than other treatments for the flu, leading experts to question why countries stockpile the medication twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production --- # Study Finds Tamiflu Not as Effective as Thought > Sponsored content. 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Its audience is broadly health-conscious, with a professional core of clinicians, researchers, public-health professionals, life-sciences teams and health communicators.  by [Alice Park](https://time.com/author/alice-park/)  ## Alice Park Senior Correspondent Apr 10, 2014 3:22 PM UTC  by [Alice Park](https://time.com/author/alice-park/)  ## Alice Park Senior Correspondent Apr 10, 2014 3:22 PM UTC Researchers say the [popular antiviral flu drugs](http://content.time.com/time/world/article/0,8599,2051114,00.html) Tamiflu and Relenza are not as effective as doctors and public health experts were led to believe, in the most comprehensive review of data on the effectiveness of the two drugs. There isn’t strong evidence to support stockpiling the products in national emergency drug depots in case of a pandemic, the researchers say. Both drugs—Tamiflu is the brand name for oseltamivir and Relenza is the brand name zanamivir—are designed to stop the influenza virus from spreading in an infected person, and claim to reduce the severity of flu symptoms and how long people are sick. The Centers for Disease Control and Prevention keeps the drugs in its stockpile for use in both seasonal and pandemic flu situations, and the European Medicines Agency (EMA) and the World Health Organization also recommend the medications for treating flu. **MORE:** [Scientists Can Now Predict the Flu](http://time.com/10560/scientists-can-now-predict-the-flu/) The authors of the current review found, however, that in the case of the European approvals in particular, regulatory agencies relied on summaries of studies rather than an exhaustive analysis of raw data, known as clinical study reports, which can run to more than 1,000 pages and detail methods, protocols and statistical analyses. After a four-year effort to obtain this data from both the manufacturers and the EMA, the authors report in the journal _BMJ_ that those trials do not support claims that the drugs lower the risk of complications from flu, such as pneumonia, or that the benefits of the drugs outweigh their risks, which include nausea, vomiting, headaches and kidney disorders. The authors point to not just one failure in the process of approving these medications, but a weak regulatory system in which the studies are all conducted by manufacturers, and in which the trials compared the medications against placebo rather than to existing flu treatments. Given that the more comprehensive review found little support for recommending oseltamivir to reduce flu symptoms or hospitalization due to complications from flu, the authors write: “We believe these findings provide reason to question the stockpiling of oseltamivir, its inclusion on the WHO list of essential drugs, and its use in clinical practice as an anti-influenza drug.” On zanamivir, they said “Our findings do not support the mode of action of zanamivir proposed by the manufacturer.” ```json [{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/57480/tamiflu-study-relenza/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/57480/tamiflu-study-relenza/"},"headline":"Study Finds Tamiflu Not as Effective as Thought","datePublished":"2014-04-10T15:22:08.000Z","dateModified":"2026-02-21T07:14:38.654Z","description":"The antiviral drug isn’t any better than other treatments for the flu, leading experts to question why countries stockpile the medication","url":"https://time.com/57480/tamiflu-study-relenza/","keywords":["Research","flu","influenza"],"thumbnailUrl":"","author":[{"@type":"Person","name":"Alice Park","jobTitle":"Senior Correspondent","url":"https://time.com/author/alice-park/"}],"articleSection":"Health","image":[],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/health/","name":"Health"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/research/","name":"Research"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/57480/tamiflu-study-relenza/","name":"Study Finds Tamiflu Not as Effective as Thought"}}]}] ```