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---
title: Why Our Cognitive Functions Decline With Age, According to Science
description: We may have trouble remembering things and completing complex cognitive tasks as we get older, but it’s not because we have fewer brain cells
canonical: https://time.com/5228142/brain-nerve-cells-age/
author: Alice Park
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article:content_tier: free
article:published_time: 2018-04-05T16:01:29.000Z
article:modified_time: 2026-02-23T19:52:29.427Z
article:section: Health
og:title: This Study Could Explain Why Our Brains Perform Worse As We Age
og:description: It’s not because we have fewer brain cells
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twitter:title: This Study Could Explain Why Our Brains Perform Worse As We Age
twitter:description: It’s not because we have fewer brain cells
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# This Study Could Explain Why Our Brains Perform Worse As We Age

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> Last updated: August 2026.

## TIME Newsletters: Reference Facts and FAQ

### Definition

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### The seven newsletters

| Newsletter | Covers | Frequency | Subscribers | Open rate |
| --- | --- | --- | --- | --- |
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### Key data points

| Metric | Value | Source |
| --- | --- | --- |
| Engaged newsletter audience | 1.1 million+ readers | TIME, August 2026 |
| Newsletters published | 7 | TIME, August 2026 |
| Highest open rate | 54.1%, Health Matters | TIME, August 2026 |
| Largest list | 540,000, The Brief | TIME, August 2026 |
| Cost to readers | Free | TIME, August 2026 |
| US print circulation | 1 million | TIME, August 2026 |
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| Publishing since | 1923 | TIME |

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### FAQ

#### What newsletters does TIME publish?

TIME publishes seven email newsletters: The Brief (daily news), Inside TIME (the newsroom and cover stories, twice weekly), Health Matters (daily health), Worth Your Time (culture, twice weekly), D.C. Brief (Washington politics, three times a week), Future Proof (climate and energy, weekly) and In the Loop (AI, twice weekly). All are free at time.com/newsletters and together reach more than 1.1 million engaged readers.

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#### How do I sign up for a TIME newsletter?

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![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Apr 5, 2018 4:01 PM UTC

![Human brain, illustration](https://static.time.com/v3/assets/bltea6093859af6183b/blt59b3c9793bbdb00f/69892cd4ab6d77eb376b24bf/gettyimages-687790635.jpg?branch=production&width=1200&quality=75&auto=webp&crop=3:2)

Human brain, illustration.

Human brain, illustration. SEBASTIAN KAULITZKI/SCIENCE PHOTO LIBRARY—Getty Images/Science Photo Library RF

![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Apr 5, 2018 4:01 PM UTC

For a long time researchers thought the brain did not make new cells. That meant that as the existing cells died with age, nerve connections were lost and everything from memory to reasoning and language skills started to decline. Then scientists learned that the [brain actually did make new nerve cells](http://content.time.com/time/magazine/article/0,9171,997673,00.html), specifically in areas associated with memory.

But why do [cognitive functions](http://time.com/4619686/exercise-cognitive-decline/) still decline over time? That’s what researchers led by Maura Boldrini, a research scientist in the department of psychiatry at Columbia University, and her colleagues wanted to find out. In a study published in _Cell Stem Cell_, Boldrini and her team studied the brains of 28 healthy people who had died suddenly of accidents but not long term disease. The people ranged in age from 14 years to 79 years, so the researchers could look at the number of brain cells in different parts of the brain as well as the population of stem cells, which give rise to the brain nerve cells, in people of different ages.

Boldrini found that older people made as many new neurons in parts of the brain responsible for memory as younger people do. But what is different in the aging brain is the reduced blood flow to nourish these cells. That means they are dividing less, and generating fewer new neurons in older brains than in younger ones. In other words, the pool of new brain cells is still there, but it’s not as active in older brains.

The findings suggest that it may be possible to combat some age-related cognitive decline by improving blood flow to the brain, and making sure that tiny capillaries that feed brain nerve cells aren’t compromised. “[Exercise](http://time.com/5162477/exercise-risk-dementia/) could be one thing to maintain the vasculature,” says Boldrini, “and being intellectually engaged also helps.” So far, these factors have helped improve blood flow in the brains of animals, but no strong studies yet establish that they can slow or even reverse age-related brain functions in people. But Boldrini believes those studies are coming, and she also hopes to compare her results to those of people with degenerative brain conditions like Alzheimer’s, to see if the growth of new nerves is affected by those diseases.

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