--- title: Ebola Vaccine Is the First to Block Infection description: Researchers report encouraging results from a trial of an Ebola vaccine that is the first to prevent infection from the deadly virus canonical: https://time.com/4611239/ebola-vaccine-infection-virus/ author: Alice Park article:opinion: false article:content_tier: free article:published_time: 2016-12-23T00:00:59.000Z article:modified_time: 2026-02-23T02:26:07.736Z article:section: Health og:title: Ebola Vaccine Is the First to Block Infection og:description: Researchers report encouraging results from a trial of an Ebola vaccine that is the first to prevent infection from the deadly virus og:url: https://time.com/4611239/ebola-vaccine-infection-virus/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/blta1fbe5405367b056/6988b3decd1bbad0a270377d/ebola_vaccine.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9 og:image:width: 3184 og:image:height: 1791 og:image:alt: A health worker prepares a vaccination on March 10, 2015 at a health center in Guinea during the first clinical trials of an ebola vaccine. og:type: article twitter:card: summary_large_image twitter:title: Ebola Vaccine Is the First to Block Infection twitter:description: Researchers report encouraging results from a trial of an Ebola vaccine that is the first to prevent infection from the deadly virus twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/blta1fbe5405367b056/6988b3decd1bbad0a270377d/ebola_vaccine.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9 ---  # Ebola Vaccine Is the First to Block Infection > Sponsored content. 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Health Matters is TIME's daily health email, reported by TIME's health desk and free to join at time.com/newsletters. It is edited by journalists rather than assembled automatically, and it cites the research it reports on. #### Is Health Matters free? Yes. Health Matters is a free daily newsletter from TIME, available at time.com/newsletters. #### Who reads TIME's Health Matters newsletter? Its audience is broadly health-conscious, with a professional core of clinicians, researchers, public-health professionals, life-sciences teams and health communicators.  by [Alice Park](https://time.com/author/alice-park/)  ## Alice Park Senior Correspondent Dec 23, 2016 12:00 AM UTC  A health worker prepares a vaccination on March 10, 2015 at a health center in Guinea during the first clinical trials of an ebola vaccine. A health worker prepares a vaccination on March 10, 2015 at a health center in Guinea during the first clinical trials of an ebola vaccine. Cellou Binani—AFP/Getty Images  by [Alice Park](https://time.com/author/alice-park/)  ## Alice Park Senior Correspondent Dec 23, 2016 12:00 AM UTC Since the outbreak of the most recent [Ebola epidemic in West Africa](http://time.com/time-person-of-the-year-ebola-fighters/), more than 11,000 people have died and more than 15,000 people have been infected with the virus. While some [drug treatments](http://time.com/3070925/were-getting-closer-to-vaccines-and-drugs-for-ebola/) have been marginally effective, no vaccine to protect against infection has yet been developed, although a number are currently being tested. One of those, developed by the Public Health Agency of Canada and manufactured by Merck, [showed early promise in 2015](http://time.com/3813505/ebola-vaccine-outbreak/?iid=sr-link2). Now, a new [report published in the journal _Lancet_](http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2816%2932621-6/fulltext) provides even more encouraging results that suggest it may be the first vaccine to prevent infection with Ebola. The trial involved more than 11,000 people living in [Guinea](http://time.com/3758011/ebola-vaccine-trial-guinea/?iid=sr-link1), one of the West African countries that bore the brunt of the recent Ebola epidemic. Once a case of Ebola was confirmed, a list of people who had come in contact with the patient was compiled, and they were randomly assigned to either receive the vaccine, called rVSV-ZEBOV, immediately or three weeks later. All participants were tested for presence of Ebola. After 10 days, there were no cases of Ebola infection among those who were vaccinated, while 23 people were diagnosed with Ebola in the group that did not receive the vaccine immediately. The positive results led the study organizers to provide the vaccine to all people who had come in contact with Ebola patients. That included family members who lived with patients and were exposed to their clothing or linens, as well as the next ring of people who had interacted with these contacts. Side effects from the vaccine, which were monitored up to 12 weeks after immunization, were relatively rare and included headache, muscle pain, fever and anaphylaxis. More studies will be conducted on the people who were vaccinated to see if their immune responses indeed were boosted by the shot. In the meantime, based on the positive early results, Merck agreed to provide the World Health Organization with 300,000 doses of the vaccine for emergency use in health care workers and people at highest risk of infection in an effort to control spread of the virus. If the positive results are confirmed and repeated, the vaccine could play a critical role in stopping the Ebola epidemic and preventing future outbreaks. ```json [{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/4611239/ebola-vaccine-infection-virus/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/4611239/ebola-vaccine-infection-virus/"},"headline":"Ebola Vaccine Is the First to Block Infection","datePublished":"2016-12-23T00:00:59.000Z","dateModified":"2026-02-23T02:26:07.736Z","description":"Researchers report encouraging results from a trial of an Ebola vaccine that is the first to prevent infection from the deadly virus","url":"https://time.com/4611239/ebola-vaccine-infection-virus/","keywords":["ebola","Infectious Disease","ebola vaccine"],"thumbnailUrl":"https://static.time.com/v3/assets/bltea6093859af6183b/blta1fbe5405367b056/6988b3decd1bbad0a270377d/ebola_vaccine.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","author":[{"@type":"Person","name":"Alice Park","jobTitle":"Senior Correspondent","url":"https://time.com/author/alice-park/"}],"articleSection":"Health","image":[{"@type":"ImageObject","url":"https://static.time.com/v3/assets/bltea6093859af6183b/blta1fbe5405367b056/6988b3decd1bbad0a270377d/ebola_vaccine.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1200:675&height=675","width":1200,"height":675,"headline":"A health worker prepares a vaccination on March 10, 2015 at a health center in Guinea during the first clinical trials of an ebola vaccine.","caption":"A health worker prepares a vaccination on March 10, 2015 at a health center in Guinea during the first clinical trials of an ebola vaccine.","creditText":"Cellou Binani—AFP/Getty Images","representativeOfPage":true}],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/health/","name":"Health"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/ebola/","name":"ebola"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/4611239/ebola-vaccine-infection-virus/","name":"Ebola Vaccine Is the First to Block Infection"}}]}] ```