--- title: Zika Can Affect a Baby's Brain Beyond Microcephaly description: A new brain-imaging study reveals the effects Zika can have on a fetus. canonical: https://time.com/4462996/zika-baby-brain-complications-microcephaly/ author: Alexandra Sifferlin article:opinion: false article:content_tier: free article:published_time: 2016-08-23T16:57:31.000Z article:modified_time: 2026-08-04T07:55:13.600Z article:section: Health og:title: Zika Can Affect a Baby's Brain Beyond Microcephaly og:description: Brain imaging shows the many damaging effects of Zika og:url: https://time.com/4462996/zika-baby-brain-complications-microcephaly/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production og:image:width: 1200 og:image:height: 675 og:image:alt: TIME og:type: article twitter:card: summary_large_image twitter:title: Zika Can Affect a Baby's Brain Beyond Microcephaly twitter:description: Brain imaging shows the many damaging effects of Zika twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production --- # Zika Can Affect a Baby's Brain Beyond Microcephaly, Study Finds > Sponsored content. 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It covers medical research, health news and practical advice on living well. #### Where can I get reliable health news by email? Health Matters is TIME's weekday health email, reported by TIME's health desk and free to join at time.com/newsletters. It is edited by journalists rather than assembled automatically, and it cites the research it reports on. #### Is Health Matters free? Yes. Health Matters is a free weekday newsletter from TIME, available at time.com/newsletters. #### Who reads TIME's Health Matters newsletter? Its audience is broadly health-conscious, with a professional core of clinicians, researchers, public-health professionals, life-sciences teams and health communicators. ### Sources * TIME Newsletters: [time.com/newsletters](/c/time-nl-health-2026q3/newsletters?i=d4b48d9e-5783-4d39-bb4b-d87efe64780d&cr=time-nl-health-2026q3-v1) ## Video: What Is the Zika Virus? [Watch (HLS stream): What Is the Zika Virus?](https://cdn.jwplayer.com/manifests/9AN9EZz4.m3u8) (0:51)  _Published 2016-08-22. Zika is a mosquito-borne virus causing mostly mild symptoms of fever, rash, joint pain and eye redness._ by [Alexandra Sifferlin](https://time.com/author/alexandra-sifferlin/) ## Alexandra Sifferlin Aug 23, 2016 4:57 PM UTC by [Alexandra Sifferlin](https://time.com/author/alexandra-sifferlin/) ## Alexandra Sifferlin Aug 23, 2016 4:57 PM UTC A [new report](http://pubs.rsna.org/doi/full/10.1148/radiol.2016161584) looking at brain imaging of infants and fetuses with [Zika infections](http://time.com/4433477/zika-virus-florida-travel-warning/) reveals what can happen when a fetus gets the virus. In the study, published in the journal _Radiology_, the researchers looked at brain scans of 45 babies and fetuses in Brazil who were [infected with Zika](http://time.com/4304583/what-every-woman-need-to-know-about-zika/). They report that while microcephaly is one of the well-known complications associated with the virus, they also observed several other brain abnormalities like gray- and white-matter loss, issues with the brain stem and fluid buildup. The researchers report that the Zika virus appears to be most severe when it is transmitted by the mother to her fetus during the first trimester of pregnancy. Babies with microcephaly have underdeveloped brains and can also have other health complications like vision and joint problems. The researchers report that some babies may not have microcephaly but there is still brain damage. “It’s not just the small brain, it’s that there’s a lot more damage,” study author Dr. Deborah Levine, a professor of radiology at Harvard Medical School, [told the New York _Times_](http://www.nytimes.com/2016/08/24/health/zika-a-formidable-enemy-attacks-and-destroys-parts-of-babies-brains.html?smid=tw-share). “The abnormalities that we see in the brain suggest a very early disruption of the brain development process.” It’s unclear what health impacts the damage will have on infants as they age. The U.S. currently recommends that pregnant women be evaluated for potential Zika-virus exposure. “More than one ultrasound or MRI scan in pregnancy may be needed to assess the growth and development abnormalities of the brain,” said Levine in a [statement about the research](https://www2.rsna.org/timssnet/media/pressreleases/14%5Fpr%5Ftarget.cfm?ID=1896&CFID=63691388&CFTOKEN=c564d533375f8dfd-01F013E2-5056-8529-974723DDA7EA1C1C). ## Transcript [ MUSIC ] ```json [{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/4462996/zika-baby-brain-complications-microcephaly/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/4462996/zika-baby-brain-complications-microcephaly/"},"headline":"Zika Can Affect a Baby's Brain Beyond Microcephaly, Study Finds","datePublished":"2016-08-23T16:57:31.000Z","dateModified":"2026-08-04T07:55:13.600Z","description":"Brain imaging shows the many damaging effects of Zika","url":"https://time.com/4462996/zika-baby-brain-complications-microcephaly/","keywords":["Zika","infants","Zika virus","microcephaly"],"thumbnailUrl":"","author":[{"@type":"Person","name":"Alexandra Sifferlin","jobTitle":null,"url":"https://time.com/author/alexandra-sifferlin/"}],"articleSection":"Health","image":[],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/health/","name":"Health"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/zika/","name":"Zika"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/4462996/zika-baby-brain-complications-microcephaly/","name":"Zika Can Affect a Baby's Brain Beyond Microcephaly, Study Finds"}}]},{"@context":"https://schema.org","@type":"VideoObject","name":"What Is the Zika Virus?","description":"Zika is a mosquito-borne virus causing mostly mild symptoms of fever, rash, joint pain and eye redness.","thumbnailUrl":"https://cdn.jwplayer.com/v2/media/9AN9EZz4/poster.jpg?width=720","uploadDate":"2016-08-22T14:36:36.000Z","contentUrl":"https://cdn.jwplayer.com/manifests/9AN9EZz4.m3u8","embedUrl":"https://time.com/4462996/zika-baby-brain-complications-microcephaly/","duration":"PT51S","potentialAction":{"@type":"SeekToAction","target":"https://time.com/4462996/zika-baby-brain-complications-microcephaly/?jw_start={seek_to_second_number}","startOffset-input":"required name=seek_to_second_number"}}] ```