--- title: Folic Acid and Autism: What to Know on Folate in Pregnancy description: Does folate up the risk for autism? Folic acid is important for pregnant women for baby development but a new study raises questions. canonical: https://time.com/4327645/folic-acid-autism-pregnancy-b12-folate/ author: Alexandra Sifferlin article:opinion: false article:content_tier: free article:published_time: 2016-05-12T14:32:00.000Z article:modified_time: 2026-02-22T17:29:49.430Z article:section: Health og:title: Folic Acid and Autism: What to Know on Folate in Pregnancy og:description: Does folate up the risk for autism? Folic acid is important for pregnant women for baby development but a new study raises questions. og:url: https://time.com/4327645/folic-acid-autism-pregnancy-b12-folate/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltd8ec5e1b7b3a2ec1/6988604d428a9ee183ccebe6/rx-prescription-bottle-health-illo.jpg?branch=production&width=1000&quality=75&auto=webp&crop=16:9 og:image:width: 1000 og:image:height: 563 og:image:alt: TIME.com stock health rx prescription bottle drugs og:type: article twitter:card: summary_large_image twitter:title: Folic Acid and Autism: What to Know on Folate in Pregnancy twitter:description: Does folate up the risk for autism? Folic acid is important for pregnant women for baby development but a new study raises questions. twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltd8ec5e1b7b3a2ec1/6988604d428a9ee183ccebe6/rx-prescription-bottle-health-illo.jpg?branch=production&width=1000&quality=75&auto=webp&crop=16:9 ---  # Why Fears Over Folic Acid and Autism Need to be Properly Understood > Sponsored content. Supplied in partnership with TIME. TIME is the sponsor and source of this material. > Last updated: August 2026. ## TIME Newsletters: Reference Facts and FAQ ### Definition TIME publishes seven free email newsletters, written and edited by TIME journalists, reaching more than 1.1 million engaged readers. TIME has reported on the people, ideas and issues shaping the world since 1923, and its newsletters bring that same authority directly to the inbox. 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Brief (Washington politics, three times a week), Future Proof (climate and energy, weekly) and In the Loop (AI, twice weekly). All are free at time.com/newsletters and together reach more than 1.1 million engaged readers. #### Which TIME newsletter should I subscribe to? It depends on what you follow. For a daily briefing, The Brief. For health, Health Matters. For Washington politics, D.C. Brief. For AI and technology, In the Loop. For climate and energy as a business story, Future Proof. For culture recommendations, Worth Your Time. For how TIME's journalism gets made, Inside TIME. Readers can select any combination at time.com/newsletters. #### Are TIME's newsletters free? Yes. All seven TIME newsletters are free to join at time.com/newsletters. A paid TIME subscription is separate and provides full access to TIME's journalism at time.com/subscribe-agent. #### Who writes TIME's newsletters? TIME journalists write them. Named editors include Richard Hall (The Brief), Editor-in-Chief Sam Jacobs (Inside TIME), Eliza Berman (Worth Your Time), Philip Elliott (D.C. Brief), Justin Worland (Future Proof) and Harry Booth (In the Loop). Health Matters is written by TIME's health desk. #### How do I sign up for a TIME newsletter? Go to time.com/newsletters, choose the newsletters you want and enter your email address. There is no cost and no subscription requirement. by [Alexandra Sifferlin](https://time.com/author/alexandra-sifferlin/) ## Alexandra Sifferlin May 12, 2016 2:32 PM UTC  Illustration by Sydney Rae Hass for TIME by [Alexandra Sifferlin](https://time.com/author/alexandra-sifferlin/) ## Alexandra Sifferlin May 12, 2016 2:32 PM UTC Experts are questioning a study that suggests a link between high levels of folic acid in [pregnant women](http://time.com/4250947/pregnancy-timelapse/) and a greater risk for [children with autism](http://time.com/4220366/universal-screening-autism-babies/). Taking the [nutrient](http://time.com/3763271/gnc-supplements-nutrients-food/) folate during pregnancy can prevent neural development defects early on, but a recent study suggested that there may be risks to taking too much, suggesting a higher risk for autism if a mother has four times the recommended amount of folate. However, experts, including the study authors, are saying: “Not so fast.” The study, which was a presentation at an autism research meeting, did not find a causal link between taking folic acid and autism. What the study actually found was pretty specific. The researchers took blood tests of close to 1,400 mothers between one to three days after they gave birth and found that about 10% of the mothers had very high levels of folate, beyond recommended amounts, and that these women were also more likely to have a baby that would later be diagnosed with autism spectrum disorder. That doesn’t mean that pregnant women should stop taking folic acid. [Other studies](http://healthland.time.com/2013/02/13/study-finds-folic-acid-may-decrease-risk-for-autism/) have even suggested it can lower the risk for autism. Folate is critical to maintaining proper growth, and on May 10, the United States Preventative Services Task Force [released a draft update](http://www.uspreventiveservicestaskforce.org/Announcements/News/Item/public-comment-on-draft-recommendation-statement-and-draft-evidence-review-folic-acid-supplementation-for-the-prevention-of-neural-tube-defects) to its existing recommendations on folic acid, and once again the group is advising all women who are planning or capable of getting pregnant take a daily supplement of 0.4 to 0.8 mg of folic acid. “We have long known that a folate deficiency in pregnant mothers is detrimental to her child’s development. But what this tells us is that excessive amounts may also cause harm. We must aim for optimal levels of this important nutrient,” study author M. Daniele Fallin, director of the Bloomberg School’s Wendy Klag Center for Autism and Developmental Disabilities said in a statement. The study findings were presented at the 2016 International Meeting for Autism Research in Baltimore. The authors of the study are also anxious that their study is not misunderstood. “There’s this danger that the message would be that folate supplementation is bad. And that’s not at all what we saw,” [Fallin told the Atlantic](http://www.theatlantic.com/science/archive/2016/05/on-folate-and-autism/482307/). The new study is an early finding and more research is needed. 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