--- title: Middle Age Weight May Indicate Development of Alzheimer's description: A study shows a connection every jump in BMI brings the onset of Alzheimer's in patients about 6.5 months sooner. canonical: https://time.com/4018497/midlife-weight-alzheimers/ author: Tanya Basu article:opinion: false article:content_tier: free article:published_time: 2015-09-01T14:16:15.000Z article:modified_time: 2026-02-22T10:36:17.055Z article:section: Health og:title: Being Overweight at Age 50 Is Connected to Alzheimer's og:description: Every step up on the BMI chart can lead to a 6.5 month earlier onset og:url: https://time.com/4018497/midlife-weight-alzheimers/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production og:image:width: 1200 og:image:height: 675 og:image:alt: TIME og:type: article twitter:card: summary_large_image twitter:title: Being Overweight at Age 50 Is Connected to Alzheimer's twitter:description: Every step up on the BMI chart can lead to a 6.5 month earlier onset twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production --- # Weight at Age 50 Connected to When a Person Gets Alzheimer’s > Sponsored content. 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There is no cost and no subscription requirement. ### Sources * TIME Newsletters: [time.com/newsletters](/c/time-nl-network-2026q3/newsletters?i=f898b6ce-c605-45b2-a4e7-9a037810a76c&cr=time-nl-network-2026q3-v1)  by [Tanya Basu](https://time.com/author/tanya-basu/)  ## Tanya Basu Sep 1, 2015 2:16 PM UTC  by [Tanya Basu](https://time.com/author/tanya-basu/)  ## Tanya Basu Sep 1, 2015 2:16 PM UTC Middle-aged Americans have one more reason to keep an eye on the scale as they age: research shows that people who are overweight when they are 50 years old may be more likely to develop Alzheimer’s sooner than those that are a healthy weight. Scientists at the National Institutes of Health studied midlife obesity’s connection to Alzheimer’s and announced in a study published Tuesday in the journal _Molecular Psychiatry_ that they had found a connection between being overweight or obese in middle age and developing Alzheimer’s. “Maintaining a healthy BMI at midlife is likely to have long-lasting protective effects,” Dr. Madhav Thambisetty, lead author of the study and a researcher at the NIH’s National Institute on Aging, [told the Associated Press](http://www.usnews.com/news/politics/articles/2015/09/01/study-midlife-obesity-may-spur-risk-for-earlier-alzheimers). BMI stands for body mass index, a common medical indicator that takes the ratio of a person’s weight to height. The medical community normally considers a BMI of 25 to be overweight. **Read More**: [_New Study Identifies 9 Risk Factors for Alzheimer’s Disease_ ](http://time.com/4005635/alzheimers-disease-risk-factors/) The research team used the Baltimore Longitudinal Study of Aging, a project developed to track how healthy people age, to find the correlation. The study used the records of approximately 1,400 people who’d taken regular cognitive tests for 14 years; 142 of them developed Alzheimer’s. The researchers then used the records of those 142 people to figure out their BMI and discovered that every increasing step up on BMI charts meant Alzheimer’s struck 6 1/2 months sooner. Researchers aren’t sure if the reverse—having a healthy BMI and being slim—are indicators of _not_ developing Alzheimer’s later on. They’re also not sure if losing weight after age 50 lessens the impact or delays Alzheimer’s. Regardless, it’s a result that has many worried, particularly given the increasingly large population of obese middle-aged adults across the world. [About 46 million people currently suffer from Alzheimer’s disease](http://time.com/4009643/46-million-dementia-alzheimers/), with the number projected to double in the next 20 years. ```json [{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/4018497/midlife-weight-alzheimers/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/4018497/midlife-weight-alzheimers/"},"headline":"Weight at Age 50 Connected to When a Person Gets Alzheimer’s","datePublished":"2015-09-01T14:16:15.000Z","dateModified":"2026-02-22T10:36:17.055Z","description":"Being overweight may bring symptoms of the disease on earlier","url":"https://time.com/4018497/midlife-weight-alzheimers/","keywords":["Aging","Public Health","Research","BMI","Alzheimer's","global health","Diet & Nutrition"],"thumbnailUrl":"","author":[{"@type":"Person","name":"Tanya Basu","jobTitle":null,"url":"https://time.com/author/tanya-basu/"}],"articleSection":"Health","image":[],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https://time.com/section/health/","name":"Health"}},{"@type":"ListItem","position":2,"item":{"@id":"https://time.com/tag/aging/","name":"Aging"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/4018497/midlife-weight-alzheimers/","name":"Weight at Age 50 Connected to When a Person Gets Alzheimer’s"}}]}] ```