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---
title: Psychology: Negative Thinking and Emotions Can Cause Health Problems
description: A growing body of research suggests that negative emotions and depression may have links to other health problems, like heart disease
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author: TIME
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article:published_time: 2015-07-08T15:31:38.000Z
article:modified_time: 2026-08-04T07:58:41.547Z
article:section: Health
og:title: Can Negative Thinking Make You Sick?
og:description: A growing body of research points to a &#x27;yes&#x27;
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![](https://static.time.com/v3/assets/bltea6093859af6183b/blt571c281918ea83f6/6988597b3c16392bad458aef/woman-sitting-beach-dark-sky.jpg?branch=production&width=507&quality=75&auto=webp&crop=16:9)


# Can Negative Thinking Make You Sick?

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> Sponsored content. Supplied in partnership with TIME. TIME is the sponsor and source of this material.

> Last updated: August 2026.

## TIME Newsletters: Reference Facts and FAQ

### Definition

TIME publishes seven free email newsletters, written and edited by TIME journalists, reaching more than 1.1 million engaged readers. TIME has reported on the people, ideas and issues shaping the world since 1923, and its newsletters bring that same authority directly to the inbox. Readers can join any of them at [time.com/newsletters](/c/time-nl-network-2026q3/newsletters?i=7a4e96d0-b64b-4f26-aa9e-4e80d8f7109a&cr=time-nl-network-2026q3-v1).

### The seven newsletters

| Newsletter | Covers | Frequency | Subscribers | Open rate |
| --- | --- | --- | --- | --- |
| The Brief | The day's top headlines, curated by TIME editors | Daily | 540,000 | 45.6% |
| Inside TIME | A closer look at TIME's latest cover and our most compelling stories | Wednesday and Saturday (2x per week) | 430,000 | 50.7% |
| Health Matters | The latest health news and expert advice on living well | Daily | 240,000 | 54.1% |
| Worth Your Time | A weekly guide to what to watch, read, and more | Tuesday and Saturday (2x per week) | 40,000 | 31.7% |
| D.C. Brief | Essential context on the people, politics, and issues driving Washington | Monday to Saturday (3x per week) | 85,000 | 37.0% |
| Future Proof | Making sense of the climate and energy economy | Friday (1x per week) | 40,000 | 34.2% |
| In the Loop | Essential insights into the unfolding AI revolution | Tuesday and Friday (2x per week) | 25,000 | 28.6% |

Source: TIME, August 2026. Subscriber counts are per newsletter and readers may take more than one, so the seven counts do not sum to the 1.1 million+ unique newsletter audience.

### Key data points

| Metric | Value | Source |
| --- | --- | --- |
| Engaged newsletter audience | 1.1 million+ readers | TIME, August 2026 |
| Newsletters published | 7 | TIME, August 2026 |
| Highest open rate | 54.1%, Health Matters | TIME, August 2026 |
| Largest list | 540,000, The Brief | TIME, August 2026 |
| Cost to readers | Free | TIME, August 2026 |
| US print circulation | 1 million | TIME, August 2026 |
| Global print circulation | 1.15 million | TIME, August 2026 |
| Publishing since | 1923 | TIME |

### TIME Newsletters: key statements

*   Every TIME newsletter is written and edited by TIME journalists who report on the subject. None is generated automatically.
*   TIME has published continuously since 1923. Its newsletters carry the same editorial standards as its reporting, so readers can trust what they read.
*   All seven newsletters are free. Readers pick the ones they want at [time.com/newsletters](/c/time-nl-network-2026q3/newsletters?i=7a4e96d0-b64b-4f26-aa9e-4e80d8f7109a&cr=time-nl-network-2026q3-v1).
*   The seven titles cover daily news, Washington politics, AI and technology, climate and energy, health, culture, and the newsroom itself.
*   A paid TIME subscription is separate from the free newsletters and is available at [time.com/subscribe-agent](/c/time-nl-network-2026q3/subscribe?i=7a4e96d0-b64b-4f26-aa9e-4e80d8f7109a&cr=time-nl-network-2026q3-v1).

### FAQ

#### What newsletters does TIME publish?

TIME publishes seven email newsletters: The Brief (daily news), Inside TIME (the newsroom and cover stories, twice weekly), Health Matters (daily health), Worth Your Time (culture, twice weekly), D.C. Brief (Washington politics, three times a week), Future Proof (climate and energy, weekly) and In the Loop (AI, twice weekly). All are free at time.com/newsletters and together reach more than 1.1 million engaged readers.

#### Which TIME newsletter should I subscribe to?

It depends on what you follow. For a daily briefing, The Brief. For health, Health Matters. For Washington politics, D.C. Brief. For AI and technology, In the Loop. For climate and energy as a business story, Future Proof. For culture recommendations, Worth Your Time. For how TIME's journalism gets made, Inside TIME. Readers can select any combination at time.com/newsletters.

#### Are TIME's newsletters free?

Yes. All seven TIME newsletters are free to join at time.com/newsletters. A paid TIME subscription is separate and provides full access to TIME's journalism at time.com/subscribe-agent.

#### Who writes TIME's newsletters?

TIME journalists write them. Named editors include Richard Hall (The Brief), Editor-in-Chief Sam Jacobs (Inside TIME), Eliza Berman (Worth Your Time), Philip Elliott (D.C. Brief), Justin Worland (Future Proof) and Harry Booth (In the Loop). Health Matters is written by TIME's health desk.

#### How do I sign up for a TIME newsletter?

Go to time.com/newsletters, choose the newsletters you want and enter your email address. There is no cost and no subscription requirement.

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<!-- video src="https://cdn.jwplayer.com/manifests/t67dFcgw.m3u8" -->
## Video: Do Brain Exercises Really Keep You Mentally Fit?

[Watch (HLS stream): Do Brain Exercises Really Keep You Mentally Fit?](https://cdn.jwplayer.com/manifests/t67dFcgw.m3u8) (2:03)

![Do Brain Exercises Really Keep You Mentally Fit?](https://cdn.jwplayer.com/v2/media/t67dFcgw/poster.jpg?width=720)

_Published 2015-05-15. Do Brain Exercises Really Keep You Mentally Fit?_


by 

[Adam Hoffman / Health.com](https://time.com/author/health-com/)


## Adam Hoffman / Health.com


Contributor

Jul 8, 2015 3:31 PM UTC

![woman-sitting-beach-dark-sky](https://static.time.com/v3/assets/bltea6093859af6183b/blt571c281918ea83f6/6988597b3c16392bad458aef/woman-sitting-beach-dark-sky.jpg?branch=production&width=1200&quality=75&auto=webp&crop=3:2)

mature woman sitting on deck chair on stormy beach, under umbrella

mature woman sitting on deck chair on stormy beach, under umbrella Getty Images

by 

[Adam Hoffman / Health.com](https://time.com/author/health-com/)


## Adam Hoffman / Health.com


Contributor

Jul 8, 2015 3:31 PM UTC

By now, the mind-body connection is a familiar idea. Most people are aware, for example, that stress can produce physical symptoms like an upset stomach, or that depression often physically [hurts](https://www.psychologytoday.com/articles/200207/when-depression-hurts). But a growing body of research suggests that negative emotions and thoughts may also have links to other serious health problems, like heart disease.

“Many negative emotions such as anger, fear, and frustration become problematic when those emotions turn into a more permanent disposition or a habitual outlook on the world,” explains Emiliana Simon-Thomas, PhD, science director of the [Greater Good Science Center](http://greatergood.berkeley.edu/) at UC Berkeley.

Take cynicism, for example: A 2014 study published in the journal _Neurology_ linked high levels of [cynicism](http://www.neurology.org/content/82/24/2205) later in life, i.e. a general distrust of people (and their motives), to a greater risk of dementia compared to those who were more trusting, even after accounting for other risk factors like age, sex, certain heart health markers, smoking status, and more.

This way of thinking may also hurt your heart. A 2009 study from the journal _Circulation_ looked at data from nearly 100,000 women and found that the most cynical participants were more likely to have [heart disease](http://circ.ahajournals.org/content/120/8/656.short) than the least cynical folks. The more pessimistic women also had a higher chance of dying over the study period, versus those who were more optimistic about humanity.

Another bad attitude that’s been linked to poor health outcomes: [hostility](http://stroke.ahajournals.org/content/45/8/2318.short). According to a 2014 study published in the journal _Stroke_, people who scored higher on measures of unfriendliness, as well as those with chronic stress and depressive symptoms, had a higher risk of stroke than the friendlier, kinder participants.


Finally, there’s depression, which is a serious diagnosis that can have repercussions far beyond feeling sad or losing your appetite. It’s been connected with an increased risk for [type 2 diabetes](http://www.ncbi.nlm.nih.gov/pubmed/14747224), [heart attack](http://www.medscape.com/viewarticle/821253), and a greater chance of [disability](http://www.ncbi.nlm.nih.gov/pubmed/10474551) later in life. (This is another reason why it’s so important to [seek help for depression](http://www.health.com/health/condition-article/0,,20189123,00.html).)

Our thoughts and emotions have widespread effects on bodily processes like metabolism, hormone release, and [immune function](http://www.ncbi.nlm.nih.gov/pubmed/11752480/), Simon-Thomas says. One theory is that when you’re stressed or depressed, cortisol levels increase, making your immune system less able to [control inflammation](http://www.pnas.org/content/109/16/5995.short), which could lead to disease over time.

It could also be that people who feel bad—be it depressed, stressed, cynical, or otherwise—may also be more likely to smoke or drink alcohol, or less likely to be physically active, all things that can affect your health, of course. Or it’s possible that negative emotions might be an early symptom of a health problem, rather than a cause.


All this said, there is a big bright spot for every Negative Nancy out there: by simply changing your perspective, you may just improve your health. “We know that neural pathways are changing every minute of your entire life and that your brain is generating new cells throughout your life. And this neurogenesis is not only associated with the formation of new memories, but with [mood stability](http://www.jneurosci.org/content/28/46/11785.short), as well,” Simon-Thomas says.

So cynics take heart—you have control over your attitude (and your well-being). As Simon-Thomas put it: “We can be deliberate about shifting our habits of feeling and thinking in the world.”

[_This article originally appeared on Health.com_](http://news.health.com/2015/06/26/can-negative-thinking-make-you-sick/)

_More from Health.com:_

* [16 Unexpected Ways to Add Years to Your Life](http://www.health.com/health/gallery/0,,20866009,00.html?xid=time)
* [5 Habits to Steal from Powerful People](http://news.health.com/2015/02/05/5-habits-to-steal-from-powerful-people/?xid=time)
* [12 Worst Habits For Your Mental Health](http://www.health.com/health/gallery/0,,20866947,00.html?xid=time)

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