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---
title: Autism: Siblings' Genetic Material Not So Similar
description: Only 30 percent of sibling pairs with autism shared the same genetic glitches
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author: Nolan Feeney
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article:published_time: 2015-01-27T00:36:13.000Z
article:modified_time: 2026-02-22T03:53:37.728Z
article:section: Health
og:title: Siblings With Autism Less Similar Than Previously Thought, Study Says
og:description: Surprising study has implications for care
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# Siblings With Autism Less Similar Than Previously Thought, Study Says

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[Nolan Feeney](https://time.com/author/nolan-feeney/)


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## Nolan Feeney


Jan 27, 2015 12:36 AM UTC

![Nolan Feeney](https://static.time.com/v3/assets/bltea6093859af6183b/blt4c014da77c72bd2e/69876bb52dce017ad89dc18d/nolan-feeney.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1:1)

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## Nolan Feeney


Jan 27, 2015 12:36 AM UTC

The majority of siblings diagnosed with autism do not share the same genetic mutation, according to [a new study](http://www.nytimes.com/2015/01/27/health/autism-diagnosis-in-siblings-serves-as-poor-indicator-of-risk.html).

Using whole-genome sequencing technology, scientists looked at the genetic material of 85 families that had two children diagnosed with autism, the New York _Times_ reports. Of those sibling pairs, about 30% shared the same genetic glitch, while roughly 70% did not. Those who shared the same genetic issue had similar habits compared to those who didn’t.

“We anticipated that, more often than not, there would be shared inheritance” said Dr. Stephen Scherer, professor of medicine at the University of Toronto and the project’s research director. “That wasn’t the case.”

Some experts say the study, which appears in the journal _Nature Medicine_, will likely lead to changes in hospitals, whose staff sometimes study the oldest child with autism to gain insight into the younger child’s diagnosis. Hospitals also use genetic profiles to advise parents about the likelihood of having another child with the same diagnosis.

“This study makes us step back and realize we’re not necessarily going to get as much predictive value out of genetic mapping as we thought,” Helen Tager-Flusberg, a Boston University developmental neuroscientist who didn’t work on the study, told the _Times_.

\[[_NYT_](http://www.nytimes.com/2015/01/27/health/autism-diagnosis-in-siblings-serves-as-poor-indicator-of-risk.html)\]

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