--- title: First Stem Cell Therapy Using Patient’s Own Skin Cells description: A Japanese woman is the first to receive retinal cells made from her own skin cells canonical: https://time.com/3340766/stem-cell-therapy-skin-cells/ author: Alice Park article:opinion: false article:content_tier: free article:published_time: 2014-09-12T16:38:25.000Z article:modified_time: 2026-02-21T10:09:32.048Z article:section: Health og:title: Woman Receives First Stem Cell Treatment Made From Her Own Skin Cells og:description: A Japanese woman is the first to receive retinal cells made from her own skin cells og:url: https://time.com/3340766/stem-cell-therapy-skin-cells/ og:site_name: TIME og:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production og:image:width: 1200 og:image:height: 675 og:image:alt: TIME og:type: article twitter:card: summary_large_image twitter:title: Woman Receives First Stem Cell Treatment Made From Her Own Skin Cells twitter:description: A Japanese woman is the first to receive retinal cells made from her own skin cells twitter:image: https://static.time.com/v3/assets/bltea6093859af6183b/bltde093bcdab65f2d0/6988d9b9bc6cfc69913e2a3c/time-logo.jpg?branch=production --- # Woman Receives First Stem Cell Therapy Using Her Own Skin Cells > Sponsored content. 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Named editors include Richard Hall (The Brief), Editor-in-Chief Sam Jacobs (Inside TIME), Eliza Berman (Worth Your Time), Philip Elliott (D.C. Brief), Justin Worland (Future Proof) and Harry Booth (In the Loop). Health Matters is written by TIME's health desk. #### How do I sign up for a TIME newsletter? Go to time.com/newsletters, choose the newsletters you want and enter your email address. There is no cost and no subscription requirement. ### Sources * TIME Newsletters: [time.com/newsletters](/c/time-nl-network-2026q3/newsletters?i=2c9cb7ec-f9e3-449b-9c44-8339652c7e31&cr=time-nl-network-2026q3-v1)  by [Alice Park](https://time.com/author/alice-park/)  ## Alice Park Senior Correspondent Sep 12, 2014 4:38 PM UTC  by [Alice Park](https://time.com/author/alice-park/)  ## Alice Park Senior Correspondent Sep 12, 2014 4:38 PM UTC Researchers at the RIKEN Center for Developmental Biology in Japan surgically transplanted a sheet of retinal pigment cells into the eye of a 70-year old woman on Friday. The cells are the first induced pluripotent stem cells, or iPS cells, given to a human patient. They were made by Masayo Takahashi, who grew them from the patient’s own skin cells, which were treated with four genetic factors to revert back to an embryonic-like state. Takahashi then soaked the cells with the appropriate growth factors and other compounds so they developed into retinal pigment cells. The patient was losing her sight due to macular degeneration, because her retinal pigment endothelial cells were damaged by an overgrowth of blood vessels. Replacing them with a new population of cells can restore her sight. **MORE:** [Stem-Cell Research: The Quest Resumes](http://content.time.com/time/magazine/article/0,9171,1874840,00.html) Stem cell scientists are starting to test their treatments in eye-related diseases, because parts of the eye are protected from the body’s immune system, which could recognize the introduced cells as foreign and destroy them. That’s not a problem with the iPS cells, since they are made from the patient’s own skin cells, but it’s an added safety net to ensure that the therapy is safe and hopefully effective. Because iPS cells are genetically treated to erase their skin cell development and revert them back to an embryonic-like state when they can become any type of cell, there are still concerns about their safety when transplanted into patients. The U.S. Food and Drug Administration has not yet approved a trial involving iPS cells – so far, [only stem cells made from excess IVF embryos have been approved](http://content.time.com/time/magazine/article/0,9171,2078130,00.html) for treating macular degeneration. A 19-member committee of the Japanese ministry of health approved the experimental procedure four days ago, according to [_Nature_](http://www.nature.com/news/next-generation-stem-cells-cleared-for-human-trial-1.15897), after Takahashi made her case, with the help of [Dr. Shinya Yamanaka](http://content.time.com/time/specials/2007/article/0,28804,1733748%5F1733754%5F1736238,00.html) of Kyoto University, who [shared the 2012 Nobel Prize for discovering iPS cells](http://healthland.time.com/2012/10/08/stem-cell-scientists-awarded-nobel-prize-in-physiology-and-medicine/). **MORE:** [Stem Cell Miracle? New Therapies May Cure Chronic Conditions like Alzheimer’s](http://content.time.com/time/magazine/article/0,9171,2078130,00.html) Japan’s stem cell scientists are hoping the surgery is a success; the field has been struggling since a well-publicized paper about a new way to make iPS cells was [retracted amid allegations of fraud](http://time.com/45541/stem-cell-scientist-guilty-of-falsifying-data/). It’s not known whether the cells will continue to grow and form abnormal tumors, or whether they will migrate to other parts of the body. But now that the first patient has received them, those questions – and more, about the effectiveness of stem cell therapy – might be answered soon. ```json [{"@context":"https://schema.org","@type":"NewsArticle","@id":"https://time.com/3340766/stem-cell-therapy-skin-cells/","mainEntityOfPage":{"@type":"WebPage","@id":"https://time.com/3340766/stem-cell-therapy-skin-cells/"},"headline":"Woman Receives First Stem Cell Therapy Using Her Own Skin Cells","datePublished":"2014-09-12T16:38:25.000Z","dateModified":"2026-02-21T10:09:32.048Z","description":"A Japanese woman is the first to receive retinal cells made from her own skin cells","url":"https://time.com/3340766/stem-cell-therapy-skin-cells/","keywords":["medicine","Stem Cells"],"thumbnailUrl":"","author":[{"@type":"Person","name":"Alice Park","jobTitle":"Senior Correspondent","url":"https://time.com/author/alice-park/"}],"articleSection":"Health","image":[],"publisher":{"@type":"Organization","name":"Time","url":"https://time.com/","logo":{"@type":"ImageObject","url":"https://time.com/images/logo.png","width":528,"height":156},"foundingDate":"March 3, 1923","sameAs":["https://www.facebook.com/time","https://www.instagram.com/time/?hl=en","https://twitter.com/time","https://www.pinterest.com/timemagazine"]}},{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/section/health/","name":"Health"}},{"@type":"ListItem","position":2,"item":{"@id":"/tag/medicine/","name":"medicine"}},{"@type":"ListItem","position":3,"item":{"@id":"https://time.com/3340766/stem-cell-therapy-skin-cells/","name":"Woman Receives First Stem Cell Therapy Using Her Own Skin Cells"}}]}] ```